Rivkin V L, Khakhanova M V, Egorov Iu N
Vopr Onkol. 1985;31(12):49-52.
A retrospective mathematic-statistical evaluation of cases of adenoma of the large intestine--asymptomatic (group 1) or bleeding one (group 2)--showed the frequency and pattern of recurrence and malignant transformation following electrocoagulation to be identical in both groups. Such change in the histologic type as transformation of tubular polyps to a villous pattern proved to be an important factor of risk for relapse and neoplastic growth of solitary adenoma of the large intestine. Villous adenoma showed the highest rate of recurrence and malignant transformation. It is considered to be obligatory precancer.
对大肠腺瘤病例(无症状组,即第1组;出血组,即第2组)进行的回顾性数学统计学评估显示,两组经电凝治疗后的复发频率和模式以及恶变情况相同。组织学类型的改变,如管状息肉转变为绒毛状模式,被证明是大肠孤立性腺瘤复发和肿瘤生长的重要风险因素。绒毛状腺瘤的复发率和恶变率最高。它被认为是癌前必发病变。