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脊髓灰质炎应急能力支持项目对建设各国能力以支持脊髓灰质炎疫情防范与应对的贡献:经验教训与尚存挑战

Polio Surge Capacity Support Program Contributions to Building Country Capacities in Support of Polio Outbreak Preparedness and Response: Lessons Learned and Remaining Challenges.

作者信息

Abebe Fikru, Eboh Victor Anochieboh, Weldetsadik Mesfin Belew, Kone Ibrahima, Kebede Tessema Assegid, Harries Paul Thomas, Diomande Veh Kesse Fabien

机构信息

Polio Surge Capacity Support Program, Center for Vaccine Equity (CVE), The Task Force for Global Health (TFGH), Decatur, GA 30030, USA.

Global Security Department (GSD), The Task Force for Global Health (TFGH), Decatur, GA 30030, USA.

出版信息

Pathogens. 2024 May 1;13(5):377. doi: 10.3390/pathogens13050377.

Abstract

Despite coordinated efforts at global level, through the Global Polio Eradication Initiative (GPEI), poliomyelitis disease (Polio) is still a major public health issue. The wild poliovirus type-1 (WPV1) is still endemic in Afghanistan and Pakistan, and new circulations of the WPV1 were confirmed in southeast Africa in 2021, in Malawi and Mozambique. The circulating vaccine derived polioviruses (cVDPV) are also causing outbreaks worldwide. The Task Force for Global Health (TFGH)'s Polio Surge Capacity Support Program, established in 2019, is an effort to reinforce the existing partnership with the GPEI to strengthen countries' capacities for polio outbreak preparedness and response. In four years, its coordinated efforts with GPEI partners have resulted in a remarkable improvement in the early detection of poliovirus circulation and reducing the missed children gaps in many countries. However, these encouraging results cannot hide an increasingly complex programmatic environment with numerous funding and operational challenges.

摘要

尽管通过全球根除脊髓灰质炎行动(GPEI)在全球层面做出了协调努力,但脊髓灰质炎疾病仍然是一个重大的公共卫生问题。野生脊髓灰质炎病毒1型(WPV1)在阿富汗和巴基斯坦仍然流行,2021年在非洲东南部的马拉维和莫桑比克确认了WPV1的新传播情况。疫苗衍生脊髓灰质炎病毒(cVDPV)也在全球范围内引发疫情。全球健康特别工作组(TFGH)于2019年设立的脊髓灰质炎应急能力支持项目,旨在加强与GPEI的现有伙伴关系,以增强各国应对脊髓灰质炎疫情的防范和应对能力。四年来,其与GPEI伙伴的协调努力已在脊髓灰质炎病毒传播的早期检测方面取得显著改善,并缩小了许多国家失查漏种儿童的差距。然而,这些令人鼓舞的成果无法掩盖一个日益复杂的项目环境,其中存在众多资金和运营方面的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91e6/11123817/522be50cd69a/pathogens-13-00377-g001.jpg

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