Bodé D D, Gelender H, Forster R K
Br J Ophthalmol. 1985 Dec;69(12):915-9. doi: 10.1136/bjo.69.12.915.
We retrospectively reviewed 28 cases of postoperative endophthalmitis due to coagulase-negative staphylococci. There was an average delay between surgery and the acute presentation of 7 X 2 days (SD 3 X 3). All patients were treated with intraocular antibiotics (IOAB) or therapeutic vitrectomy with IOAB. In six of the 28 cases the organisms were resistant to gentamicin as measured by the Kirby-Bauer technique; none was resistant to cephalosporins. Isolates that had been stored by lyophilisation were reconstituted and tested by serial dilution; none was resistant to gentamicin, though two were borderline. The final visual acuity was 6/18 or better in 72% of the eyes.
我们回顾性分析了28例由凝固酶阴性葡萄球菌引起的术后眼内炎病例。手术与急性发病之间的平均间隔时间为7±2天(标准差3±3)。所有患者均接受了眼内抗生素治疗(IOAB)或联合IOAB的治疗性玻璃体切除术。通过 Kirby-Bauer 技术检测,28例中有6例的病原菌对庆大霉素耐药;无一例对头孢菌素耐药。冻干保存的分离株经复溶后通过系列稀释法进行检测;虽有两株为临界耐药,但无一株对庆大霉素耐药。72%的患眼最终视力达到6/18或更好。