HCA Medical City Plano Graduate Medical Education, Plano, Texas, USA.
Dow University of Health Sciences Karachi, Sindh, Pakistan.
Arch Dermatol Res. 2024 May 24;316(6):210. doi: 10.1007/s00403-024-02949-7.
Basal Cell Carcinoma (BCC) is the most prevalent skin cancer and continues to witness a surge in incidence rates. The categorization of BCC subtypes into low or high risk, guided by recurrence and invasiveness metrics, underscores the need for precise differentiation. While the punch biopsy remains the gold standard for diagnosis, its invasiveness prompts a need for non-invasive alternatives. Ultrasound (US) has emerged as a noteworthy candidate, gaining momentum in its potential to offer a less intrusive diagnostic approach. We conducted a systematic review regarding features of the high-risk subtypes of BCC on US. A thorough literature search of PubMed Medline, Embase, and CINAHL databases was conducted according to PRISMA guidelines and a total of nine studies meeting our inclusion criteria were included in this review. Evidence is still nascent but US features such as lesional shape, depth, hyperechoic spots, and color doppler may be helpful in differentiating high-risk BCC subtypes. However, further prospective studies with standardized interventions and outcome measures are required.
基底细胞癌（BCC）是最常见的皮肤癌，其发病率仍在持续上升。根据复发和侵袭性指标，将 BCC 亚型分为低风险或高风险，这凸显了精确区分的必要性。虽然打孔活检仍然是诊断的金标准，但因其具有侵袭性，因此需要寻找非侵入性的替代方法。超声（US）已成为一种备受关注的候选方法，其在提供侵入性较小的诊断方法方面具有很大的潜力。我们就 US 在 BCC 高危亚型中的特征进行了系统评价。根据 PRISMA 指南，对 PubMed Medline、Embase 和 CINAHL 数据库进行了全面的文献检索，共纳入了符合纳入标准的 9 项研究。目前证据还不成熟，但 US 的特征，如病变形状、深度、高回声点和彩色多普勒，可能有助于区分高危 BCC 亚型。然而，需要进一步开展具有标准化干预措施和结局指标的前瞻性研究。
