School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China; Key Laboratory of Advanced Textile Composite of Ministry of Education, Tiangong University, Tianjin 300387, China.
College of Mechanical and Electronic Engineering, China University of Petroleum (East China), Qingdao 266580, China.
Colloids Surf B Biointerfaces. 2024 Aug;240:113970. doi: 10.1016/j.colsurfb.2024.113970. Epub 2024 May 23.
Extracts of traditional Chinese herbs (TCH) contain a variety of anti-allergic, anti-inflammatory and other bioactive factors. However, the defect of easy degradation or loss of active ingredients limits its application in traditional Chinese medicines (TCM) loaded textiles. In this work, TCH extracts containing different active ingredients were innovatively proposed as the core material of microcapsules. The feasibility of microencapsulation of multi-component TCH extracts in the essential oil state was initially demonstrated. Polyacrylate was also used as a binder to load the microcapsules onto the fabric to improve the durability and wash resistance of the treated fabric. Modeling the oil release of microcapsules for controlled release under different conditions may provide new possible uses for the materials. Results show that the constructed microcapsule has a smooth surface without depression and can be continuously released for over 30 days. The release behavior of microcapsules follows different release mechanisms and can be modulated by temperature and water molecules. The incorporation of microcapsules and polyacrylate does not significantly change the fabric's air permeability, water vapor transmission and hydrophilicity. The washing durability and friction properties of the microcapsule-based fabric are greatly improved, and it can withstand 30 washing tests and 200 friction tests. Moreover, the results of methyl thiazolyl tetrazolium (MTT) release assay using human dermal papilla cells (HDP) as an in vitro template confirm that the microcapsule has no toxic effects on human cells. Therefore, the successful microencapsulation of multi-component TCH extracts indicates their potential application in the field of TCM-loaded textiles.
中草药提取物（TCH）含有多种抗过敏、抗炎和其他生物活性因子。然而，其活性成分易降解或损失的缺陷限制了其在中药（TCM）载药纺织品中的应用。在这项工作中，创新性地提出了含有不同活性成分的 TCH 提取物作为微胶囊的核心材料。初步证明了多组分 TCH 提取物在精油状态下微胶囊化的可行性。还使用聚丙烯酸酯作为粘合剂将微胶囊负载到织物上，以提高处理过的织物的耐用性和耐洗性。对微胶囊在不同条件下的控释油释放进行建模，可能为这些材料提供新的可能用途。结果表明，构建的微胶囊表面光滑，无凹陷，可以持续释放 30 天以上。微胶囊的释放行为遵循不同的释放机制，可以通过温度和水分子进行调节。微胶囊和聚丙烯酸酯的掺入不会显著改变织物的透气性、水蒸气传输性和润湿性。基于微胶囊的织物的耐洗性和摩擦性能得到了极大的提高，可以承受 30 次洗涤测试和 200 次摩擦测试。此外，用人真皮乳头细胞（HDP）作为体外模板进行噻唑蓝（MTT）释放测定的结果证实，微胶囊对人体细胞没有毒性作用。因此，多组分 TCH 提取物的成功微胶囊化表明它们在中药载药纺织品领域具有潜在的应用前景。
