Tiralongo Francesco, Toscano Stefano, Mosconi Cristina, Iezzi Roberto, Giurazza Francesco, Castiglione Davide Giuseppe, Falsaperla Daniele, Vacirca Francesco, Ini' Corrado, Corvino Fabio, Lavalle Salvatore, Venturini Massimo, Foti Pietro Valerio, Palmucci Stefano, Basile Antonio
Radiology Unit 1, Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University Hospital Policlinico "G. Rodolico-San Marco", University of Catania, Catania, 95123, Italy.
Department of Radiology, IRCCS Azienda Ospedaliero Universitaria Di Bologna, via Albertoni 15, Bologna, 40138, Italy.
CVIR Endovasc. 2024 May 25;7(1):50. doi: 10.1186/s42155-024-00462-6.
The purpose of this systematic review and meta-analysis was to evaluate the safety, technical, and clinical effectiveness of percutaneous Transarterial Embolization (TAE) in treating spontaneous retroperitoneal hematomas as well as assess treatment outcomes in patients who underwent target or empirical embolization.
Through the PubMed, Embase, and Google Scholar databases, an extensive search was performed in the fields of spontaneous retroperitoneal hematomas treated with transcatheter arterial embolization. We collected pooled data on 141 patients from 6 separate articles selected according to the inclusion and exclusion criteria.
Technical success rate was 100% in all six studies, for both targeted and empirical embolization. The clinical success rate varied from 56.3 to 89.5%. The total number of complications related to the embolization procedure was 10 events out of 116 procedures analyzed. Empirical or empirical embolization was performed in three studies, where the source of active bleeding was not evident during DSA. A meta-analysis compared the rebleeding rates between targeted and empirical embolization groups. The odds ratio from pooled data from the three assessed studies (72 patients) showed no significant difference in rebleeding rates after empirical TAE compared with targeted TAE.
TAE is a safe, effective, and potentially life-saving procedure for the treatment of life-threatening spontaneous retroperitoneal hematomas. Empirical and targeted TAE procedures demonstrate a relatively low risk of complications, compared to the high technical and relatively high clinical success rates.
本系统评价和荟萃分析旨在评估经皮经动脉栓塞术(TAE)治疗自发性腹膜后血肿的安全性、技术及临床有效性,并评估接受靶向或经验性栓塞治疗患者的治疗效果。
通过PubMed、Embase和谷歌学术数据库,在经导管动脉栓塞治疗自发性腹膜后血肿领域进行了广泛检索。我们根据纳入和排除标准,从6篇独立文章中收集了141例患者的汇总数据。
在所有6项研究中,靶向栓塞和经验性栓塞的技术成功率均为100%。临床成功率在56.3%至89.5%之间。在分析的116例栓塞手术中,与栓塞手术相关的并发症总数为10例。3项研究进行了经验性或经验性栓塞,在数字减影血管造影(DSA)期间未发现活动性出血来源。一项荟萃分析比较了靶向栓塞组和经验性栓塞组之间的再出血率。来自3项评估研究(72例患者)的汇总数据的比值比显示,与靶向TAE相比,经验性TAE后的再出血率无显著差异。
TAE是治疗危及生命的自发性腹膜后血肿的一种安全、有效且可能挽救生命的手术。与高技术成功率和相对较高的临床成功率相比,经验性和靶向性TAE手术的并发症风险相对较低。