State Key Laboratory of Targeting Oncology, National Center for International Research of Bio-Targeting Theranostics, Guangxi Key Laboratory of Bio-Targeting Theranostics, Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning 530021, China.
Molecules. 2024 May 13;29(10):2295. doi: 10.3390/molecules29102295.
Vitamin C (VC), also known as ascorbic acid, plays a crucial role as a water-soluble nutrient within the human body, contributing to a variety of metabolic processes. Research findings suggest that increased doses of VC demonstrate potential anti-tumor capabilities. This review delves into the mechanisms of VC absorption and its implications for cancer management. Building upon these foundational insights, we explore modern delivery systems for VC, evaluating its use in diverse cancer treatment methods. These include starvation therapy, chemodynamic therapy (CDT), photothermal/photodynamic therapy (PTT/PDT), electrothermal therapy, immunotherapy, cellular reprogramming, chemotherapy, radiotherapy, and various combination therapies.
维生素 C（VC），又称抗坏血酸，作为人体内一种重要的水溶性营养物质，参与多种代谢过程。研究发现，增加 VC 剂量具有潜在的抗肿瘤能力。本综述深入探讨了 VC 的吸收机制及其在癌症管理中的意义。在此基础上，我们探讨了 VC 的现代传递系统，评估其在各种癌症治疗方法中的应用。这些方法包括饥饿疗法、化学动力学疗法（CDT）、光热/光动力疗法（PTT/PDT）、电热疗法、免疫疗法、细胞重编程、化学疗法、放射疗法以及各种联合疗法。
