Hansman D, Morris S, Gregory M, McDonald B
J Hyg (Lond). 1985 Dec;95(3):677-84. doi: 10.1017/s0022172400060782.
In Alice Springs and its vicinity, a single nasal swab was collected from 282 Australian aborigines in May 1981 to determine nasal carriage rates of pneumococci. Each swab was inoculated on blood agar and on gentamicin blood agar. The carriage rates were 89% in children, 39% in adolescents and 34% in adults. In all, 27 serotypes of pneumococci were met with and 15 (4%) of subjects yielded two or more serotypes. In children, types 23, 19, 6, 22 and 6 were predominant (in that order), whereas type 3 was commonest in older subjects. Approximately 25% children and 5% adults yielded drug-insensitive pneumococci. Resistance to benzylpenicillin, tetracycline and co-trimoxazole was met with, resistant pneumococci showed five resistance patterns and belonged to nine serotypes, predominantly types 19 and 23. All isolates were sensitive to chloramphenicol, erythromycin, lincomycin and rifampicin. The carriage rate of drug-insensitive pneumococci was 100-fold higher amongst children sampled than in non-aboriginal children in Australia.
1981年5月,在爱丽丝泉及其周边地区,从282名澳大利亚原住民中采集了单份鼻拭子,以确定肺炎球菌的鼻腔携带率。每份拭子接种于血琼脂和庆大霉素血琼脂上。儿童携带率为89%,青少年为39%,成人为34%。共发现27种肺炎球菌血清型,15名(4%)受试者分离出两种或更多血清型。在儿童中,23、19、6、22和6型最为常见(按此顺序),而3型在年长受试者中最为常见。约25%的儿童和5%的成人分离出对药物不敏感的肺炎球菌。发现对苄青霉素、四环素和复方新诺明耐药,耐药肺炎球菌呈现五种耐药模式,属于九种血清型,主要是19和23型。所有分离株对氯霉素、红霉素、林可霉素和利福平敏感。在澳大利亚,采样的儿童中对药物不敏感的肺炎球菌携带率比非原住民儿童高100倍。