Makary Christian, Menhall Abdallah, Lahoud Pierre, Yang Kyung Ran, Park Kwang Bum, Razukevicius Dainius, Traini Tonino
Oral Surgery Department, Saint Joseph University, Beirut P.O. Box 1104-2020, Lebanon.
Daegu Mir Dental Hospital, Daegu 41934, Republic of Korea.
Materials (Basel). 2024 May 14;17(10):2331. doi: 10.3390/ma17102331.
Titanium implants undergo an aging process through surface hydrocarbon deposition, resulting in decreased wettability and bioactivity. Plasma treatment was shown to significantly reduce surface hydrocarbons, thus improving implant hydrophilicity and enhancing the osseointegration process. This study investigates the effect of plasma surface treatment on bone-to-implant contact (BIC) of implants presenting a nanostructured calcium-incorporated surface (XPEED). Following a Randomized Controlled Trial (RCT) design, patients undergoing implant surgery in the posterior maxilla received additional plasma-treated (n = 7) or -untreated (n = 5) 3.5 × 8 mm implants that were retrieved after a 4-week healing period for histological examination. Histomorphometric analysis showed that plasma-treated implants exhibited a 38.7% BIC rate compared to 22.4% of untreated implants ( = 0.002), indicating enhanced osseointegration potential. Histological images also revealed increased bone formation and active osteoblastic activity around plasma-treated implants when compared to untreated specimens. The findings suggest that plasma treatment improves surface hydrophilicity and biological response, facilitating early bone formation around titanium implants. This study underscores the importance of surface modifications in optimizing implant integration and supports the use of plasma treatment to enhance osseointegration, thereby improving clinical outcomes in implant dentistry and offering benefits for immediate and early loading protocols, particularly in soft bone conditions.
钛植入物会通过表面碳氢化合物沉积经历老化过程，导致润湿性和生物活性降低。已表明等离子体处理可显著减少表面碳氢化合物，从而改善植入物的亲水性并增强骨整合过程。本研究调查了等离子体表面处理对具有纳米结构钙掺入表面（XPEED）的植入物的骨-植入物接触（BIC）的影响。按照随机对照试验（RCT）设计，在上颌后牙区接受植入手术的患者接受了额外的经等离子体处理（n = 7）或未处理（n = 5）的3.5×8 mm植入物，在4周愈合期后取出进行组织学检查。组织形态计量学分析表明，经等离子体处理的植入物的BIC率为38.7%，而未处理的植入物为22.4%（P = 0.002），表明骨整合潜力增强。与未处理的标本相比，组织学图像还显示经等离子体处理的植入物周围的骨形成增加且成骨细胞活性活跃。研究结果表明，等离子体处理可改善表面亲水性和生物学反应，促进钛植入物周围的早期骨形成。本研究强调了表面改性在优化植入物整合中的重要性，并支持使用等离子体处理来增强骨整合，从而改善种植牙科的临床结果，并为即刻和早期加载方案带来益处，特别是在软骨质条件下。
