Albahri Ghosoon, Badran Adnan, Abdel Baki Zaher, Alame Mohamad, Hijazi Akram, Daou Anis, Baydoun Elias
Plateforme de Recherche et d'Analyse en Sciences de l'Environnement (EDST-PRASE), Beirut P.O. Box 657314, Lebanon.
Department of Nutrition, University of Petra Amman Jordan, Amman P.O. Box 961343, Jordan.
Pharmaceuticals (Basel). 2024 Apr 30;17(5):574. doi: 10.3390/ph17050574.
Globally, cancer is one of the primary causes of both morbidity and mortality. To prevent cancer from getting worse, more targeted and efficient treatment plans must be developed immediately. Recent research has demonstrated the benefits of natural products for several illnesses, and these products have played a significant role in the development of novel treatments whose bioactive components serve as both chemotherapeutic and chemo-preventive agents. Phytochemicals are naturally occurring molecules obtained from plants that have potential applications in both cancer therapy and the development of new medications. These phytochemicals function by regulating the molecular pathways connected to the onset and progression of cancer. Among the specific methods are immune system control, inducing cell cycle arrest and apoptosis, preventing proliferation, raising antioxidant status, and inactivating carcinogens. A thorough literature review was conducted using Google Scholar, PubMed, Scopus, Google Patent, Patent Scope, and US Patent to obtain the data. To provide an overview of the anticancer effects of several medicinal plants, including , , , , , , , , , , , , , , L., their availability, classification, active components, pharmacological activities, signaling mechanisms, and potential side effects against the most common cancer types were explored.
在全球范围内,癌症是发病和死亡的主要原因之一。为防止癌症恶化,必须立即制定更具针对性和高效的治疗方案。最近的研究表明天然产物对多种疾病有益,这些产品在新型治疗方法的开发中发挥了重要作用,其生物活性成分可作为化疗和化学预防剂。植物化学物质是从植物中获得的天然存在的分子,在癌症治疗和新药物开发中都有潜在应用。这些植物化学物质通过调节与癌症发生和发展相关的分子途径发挥作用。具体方法包括免疫系统控制、诱导细胞周期停滞和凋亡、防止增殖、提高抗氧化状态以及使致癌物失活。使用谷歌学术、PubMed、Scopus、谷歌专利、专利范围和美国专利进行了全面的文献综述以获取数据。为了概述几种药用植物的抗癌作用,包括 , , , , , , , , , , , , , L.,探讨了它们的可用性、分类、活性成分、药理活性、信号传导机制以及对最常见癌症类型的潜在副作用。