Institute of Neurofeedback and tDCS Poland, 70-393 Szczecin, Poland.
Department of Family and Pediatric Nursing, Faculty of Health Sciences, Wrocław Medical University, 51-618 Wrocław, Poland.
Nutrients. 2024 May 17;16(10):1521. doi: 10.3390/nu16101521.
Binge eating disorder (BED) is the most common eating disorder among those contributing to the development of obesity, and thus acts as a significant burden on the lives and health of patients. It is characterized by complex neurobiology, which includes changes in brain activity and neurotransmitter secretion. Existing treatments are moderately effective, and so the search for new therapies that are effective and safe is ongoing.
This review examines the use of transcranial direct current stimulation (tDCS) in the treatment of binge eating disorder. Searches were conducted on the PubMed/Medline, Research Gate, and Cochrane databases.
Six studies were found that matched the review topic. All of them used the anodal stimulation of the right dorsolateral prefrontal cortex (DLPFC) in BED patients. tDCS proved effective in reducing food cravings, the desire to binge eat, the number of binging episodes, and food intake. It also improved the outcomes of inhibitory control and the treatment of eating disorder psychopathology. The potential mechanisms of action of tDCS in BED are explained, limitations in current research are outlined, and recommendations for future research are provided.
Preliminary evidence suggests that the anodal application of tDCS to the right DLPFC reduces the symptoms of BED. However, caution should be exercised in the broader use of tDCS in this context due to the small number of studies performed and the small number of patients included. Future studies should incorporate neuroimaging and neurophysiological measurements to elucidate the potential mechanisms of action of tDCS in BED.
暴食症(BED)是导致肥胖的最常见的饮食失调症之一,因此对患者的生活和健康造成了重大负担。它的特征是复杂的神经生物学,包括大脑活动和神经递质分泌的变化。现有的治疗方法效果中等,因此仍在寻找有效且安全的新疗法。
本综述考察了经颅直流电刺激(tDCS)在治疗暴食症中的应用。在 PubMed/Medline、Research Gate 和 Cochrane 数据库中进行了检索。
共发现 6 项符合综述主题的研究。所有研究均在暴食症患者的右侧背外侧前额叶皮层(DLPFC)使用阳极刺激。tDCS 被证明能有效减少食物渴望、暴食欲望、暴食发作次数和食物摄入量。它还改善了抑制控制的结果和饮食障碍的心理病理学的治疗效果。解释了 tDCS 在暴食症中的潜在作用机制,概述了当前研究的局限性,并提出了未来研究的建议。
初步证据表明,将 tDCS 的阳极应用于右侧 DLPFC 可减轻暴食症的症状。然而,由于进行的研究数量较少,纳入的患者数量较少,因此在这方面更广泛地使用 tDCS 时应谨慎。未来的研究应结合神经影像学和神经生理学测量,以阐明 tDCS 在暴食症中的潜在作用机制。