Department of Dermatology, George Washington University School of Medicine and Health Sciences, Suite 2B-425, 2150 Pennsylvania Avenue NW, Washington, DC, 20037, USA.
Arch Dermatol Res. 2024 May 25;316(6):254. doi: 10.1007/s00403-024-03013-0.
Asthma is one of the most well-recognized comorbidities of atopic dermatitis (AD). However, the relationship of AD severity and morphology with asthma characteristics in adults is not well defined.
To understand associations of AD severity and morphology with comorbid asthma age-of-onset and control in adults with AD.
A cross-sectional, dermatology practice-based study was performed in adults (≥ 18 years) with AD and history of asthma (N = 252). Self-administered electronic questionnaires were completed by patients, including demographics, patient-reported outcomes measures of AD severity, history of asthma, age-of-onset, and Asthma Control Test (ACT). Multivariable logistic regression models were constructed to examine relationships between AD severity and morphology with asthma age-of-onset and control.
The mean ± standard deviation ACT score was 21.7 ± 4.3 (range 5-25), with 55 (21.8%) having ACT scores ≤ 19 indicating poorly controlled asthma. AD severity and morphology were not associated with adult-onset asthma or poor asthma control.
AD severity and morphology were not consistently associated with comorbid asthma age-of-onset or control in adults with AD.
哮喘是特应性皮炎（AD）最常见的合并症之一。然而，成人 AD 的严重程度和形态与哮喘特征之间的关系尚未明确。
了解 AD 的严重程度和形态与成人 AD 合并哮喘发病年龄和控制的关系。
进行了一项横断面、基于皮肤科实践的研究，纳入了有哮喘病史的成年（≥18 岁）AD 患者（N=252）。患者通过自我管理的电子问卷完成了调查，包括人口统计学、AD 严重程度的患者报告结局测量、哮喘病史、发病年龄和哮喘控制测试（ACT）。采用多变量逻辑回归模型来检验 AD 严重程度和形态与哮喘发病年龄和控制之间的关系。
平均±标准差 ACT 评分为 21.7±4.3（范围 5-25），其中 55 名（21.8%）的 ACT 评分≤19，表明哮喘控制不佳。AD 的严重程度和形态与成人发病的哮喘或哮喘控制不佳无明显相关性。
AD 的严重程度和形态与成人 AD 合并哮喘的发病年龄或控制无明显相关性。
