Garcia P, Unal D, Panuel M, Souquet J M
Pediatrie. 1985 Sep;40(6):451-9.
Four cases of neonatal haemophilus influenzae have been reported in Intensive Care Unite of Timone's Hospital (Marseille) during a 2 year period. Three of the cases were due to non typable organism, one was a type III. Hemoculture was positive twice. None of the patients had meningitis. Clinically it was a neonatal septicemia without particularity. Prognosis is bad (50% mortality). Several hypothesis have been proposed to explain the increase of the frequency of this neonatal infection. One of the major problem is the choice and the moment of prescription of antibiotherapy.
在两年时间里,蒂莫内医院(马赛)的重症监护病房报告了4例新生儿流感嗜血杆菌感染病例。其中3例由不可分型菌株引起,1例由Ⅲ型菌株引起。血培养两次呈阳性。所有患者均未患脑膜炎。临床上表现为无特殊情况的新生儿败血症。预后不良(死亡率50%)。已提出几种假说以解释这种新生儿感染发病率的上升。主要问题之一是抗生素治疗的选择和用药时机。