Martinotti M G, Savoia D
G Batteriol Virol Immunol. 1985 Jan-Jun;78(1-6):52-9.
Studies were conducted to determine the effect of some steroid hormones, particularly sex hormones, on the growth of Trichomonas vaginalis "in vitro". 17 alpha-estradiol and 17 beta-estradiol were stimulatory for parasite growth, progesterone and testosterone were inhibiting, whereas cholesterol and ergosterol lacked such effects. Changes on the growth of T. vaginalis were observed in the first 20 hours of incubation with specific hormonal concentrations. These observations confirm the influence of sex hormones on the pathogenesis of trichomoniasis.
开展了多项研究以确定某些类固醇激素,特别是性激素,对阴道毛滴虫“体外”生长的影响。17α-雌二醇和17β-雌二醇对寄生虫生长有刺激作用,孕酮和睾酮有抑制作用,而胆固醇和麦角固醇则无此类作用。在特定激素浓度孵育的最初20小时内观察到阴道毛滴虫生长的变化。这些观察结果证实了性激素对滴虫病发病机制的影响。