Karadag Ayse Serap, Parish Lawrence Charles
Department of Dermatology and Cutaneous Biology and Jefferson Center for International Dermatology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
Department of Dermatology and Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey.
Clin Dermatol. 2018 Mar-Apr;36(2):275-277. doi: 10.1016/j.clindermatol.2017.09.011. Epub 2017 Sep 8.
Seborrheic keratosis (SK), whose appearance is generally a small roundish reddish to brownish scaling lesion ranging in size from a few mm to many mm, may have a single presentation or be one of many such lesions. Because it is a commonly encountered lesion on the face, trunk, or extemities and is readily recognized clinically, it is infrequently biopsied. When the lesion has an unusual pattern or has become irritated, it may rarely mimic a malignancy,Most patients ignore such common age spots; however, others may have concern about their appearence, in which case the SKs have been surgicaly excised. In recent retrospective studies and case reports, SKs have rarely been found to have malignant characteristics. Although these studies are inconclusive, lesions that are inflamed, bleeding, ulcerated, or sufficiently irritated may require being biopsied to rule out melanoma or other malignancies.
脂溢性角化病(SK),其外观通常是一个小的圆形,颜色从微红到褐色,有鳞屑,大小从几毫米到许多毫米不等,可能单个出现,也可能是众多此类损害之一。由于它是面部、躯干或四肢常见的损害,临床易于识别,所以很少进行活检。当损害有不寻常的形态或受到刺激时,它可能很少会酷似恶性肿瘤。大多数患者忽略这些常见的老年斑;然而,其他人可能会担心其外观,在这种情况下,脂溢性角化病会被手术切除。在最近的回顾性研究和病例报告中,很少发现脂溢性角化病具有恶性特征。尽管这些研究尚无定论,但有炎症、出血、溃疡或受到充分刺激的损害可能需要进行活检以排除黑色素瘤或其他恶性肿瘤。