Arianti Alia, Rusmayani Emma, Viona Viona
Department of Neuro-Ophthalmology, Jakarta Eye Center (JEC) Eye Hospitals and Clinics, Jakarta, Indonesia.
Department of Glaucoma, Jakarta Eye Center (JEC) Eye Hospitals and Clinics, Jakarta, Indonesia.
Int Med Case Rep J. 2024 May 20;17:507-519. doi: 10.2147/IMCRJ.S458142. eCollection 2024.
This case series aims to report the manifestation of acute secondary optic neuropathy attributed to optic nerve injury associated with a singular episode of markedly elevated intraocular pressure (IOP) during an acute glaucoma attack. The correlation between acute primary angle-closure (APAC) and non-arteritic anterior ischemic optic neuropathy (NAION) remains uncertain within the context of current knowledge. Definitive conclusions regarding the causal relationship between APAC and NAION or their mutual influence cannot be established based on the current evidence. The association between these conditions is recognized as a potential link, and comprehensive research is imperative to elucidate their interrelationship thoroughly. This case series emphasizes the importance of promptly addressing acute optic nerve injury and neuropathy associated with elevated intraocular pressure (IOP) in patients with crowded disc anatomical risk factors. It underscores the need for proactive interventions to prevent irreversible damage, highlighting the infrequent yet vision-compromising occurrence of non-arteritic anterior ischemic optic neuropathy (NAION) in acute primary angle-closure (APAC).
本病例系列旨在报告急性青光眼发作期间，因单次眼压（IOP）显著升高导致视神经损伤所致急性继发性视神经病变的表现。在当前认知背景下，急性原发性闭角型青光眼（APAC）与非动脉炎性前部缺血性视神经病变（NAION）之间的相关性仍不明确。基于现有证据，无法就APAC与NAION之间的因果关系或它们的相互影响得出明确结论。这些病症之间的关联被认为是一个潜在联系，必须进行全面研究以彻底阐明它们的相互关系。本病例系列强调了在具有视盘拥挤解剖学危险因素的患者中，及时处理与眼压（IOP）升高相关的急性视神经损伤和神经病变的重要性。它强调了采取积极干预措施以防止不可逆转损害的必要性，突出了急性原发性闭角型青光眼（APAC）中不常见但会损害视力的非动脉炎性前部缺血性视神经病变（NAION）的发生情况。
