Acan Durgul, Cakar Beyza Betul, Karahan Eyyup
Department of Ophthalmology, Balıkesir University School of Medicine, Balıkesir, Türkiye.
Front Ophthalmol (Lausanne). 2025 May 20;5:1554279. doi: 10.3389/fopht.2025.1554279. eCollection 2025.
This study aimed to compare the anterior chamber depth (ACD), anterior chamber volume (ACV), and iridocorneal angle (ICA) of the eyes of patients with non-arteritic anterior ischemic optic neuropathy (NAION) and normal eyes.
In this cross-sectional study, 28 patients with NAION who were admitted to our institution were examined. Central corneal thickness (CCT), ACV, ACD, and ICA of all eyes were measured using corneal topography (Sirius, CSO, Italy). Axial lengths (ALs) were measured using an IOL-Master 500 (Carl Zeiss, Meditec). The eyes of these patients were compared with the eyes of 29 healthy individuals of similar age and gender.
The mean ALs of the eyes with NAION and those in the control group were not statistically different, measuring 22.95 ± 0.68 mm and 23.13 ± 0.80mm, respectively (p=0.651). While the average ACV was 137.93 ± 41.01 mm in the control group, it was significantly lower at 117.86 ± 22.23 mm in the patients with NAION (p=0.038). The mean ACD, ICA, and CCT values in the control and study groups were not statistically different, with 2.82 ± 0.57 mm and 2.64 ± 0.31 mm, 41.62 ± 6.99° and 40.14 ± 7.04°, and 542.48 ± 19.39µm and 544.68 ± 31.26 µm, respectively (p1 = 0.236, p2 = 0.693, and p3 = 0.959). No statistical differences were found between the eyes with NAION and their fellow eyes in terms of AL, CCT, ACD, ACV, and ICA (p>0.05).
Differences in anterior segment morphology were observed in eyes with NAION compared to healthy eyes. Decreased ACV may be a risk factor for NAION.
本研究旨在比较非动脉炎性前部缺血性视神经病变（NAION）患者与正常眼的前房深度（ACD）、前房容积（ACV）和虹膜角膜角（ICA）。
在这项横断面研究中，对我院收治的28例NAION患者进行了检查。使用角膜地形图仪（Sirius，意大利CSO公司）测量所有眼睛的中央角膜厚度（CCT）、ACV、ACD和ICA。使用IOL-Master 500（德国卡尔蔡司医疗技术公司）测量眼轴长度（AL）。将这些患者的眼睛与29名年龄和性别相似的健康个体的眼睛进行比较。
NAION患者组和对照组的平均AL无统计学差异，分别为22.95±0.68mm和23.13±0.80mm（p = 0.651）。对照组的平均ACV为137.93±41.01mm，而NAION患者组显著降低，为117.86±22.23mm（p = 0.038）。对照组和研究组的平均ACD、ICA和CCT值无统计学差异，分别为2.82±0.57mm和2.64±0.31mm、41.62±6.99°和40.14±7.04°、542.48±19.39µm和544.68±31.26µm（p1 = 0.236，p2 = 0.693，p3 = 0.959）。NAION患者的患眼与其对侧眼在AL、CCT、ACD、ACV和ICA方面无统计学差异（p>0.05）。
与健康眼相比，NAION患者的眼前节形态存在差异。ACV降低可能是NAION的一个危险因素。
