Ye Junrong, Pan Yuanxin, Wu Chenxin, Hu Zhanhua, Wu Shengwei, Wang Wen, Guo Jianxiong, Xiao Aixiang
Geriatric Neuroscience Center, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.
Guangzhou Medical University, School of Nursing, Guangzhou, China.
Alpha Psychiatry. 2024 Jan 1;25(1):1-8. doi: 10.5152/alphapsychiatry.2024.231379. eCollection 2024 Jan.
This study aims to assess the efficacy of mindfulness-based cognitive therapy (MBCT) in alleviating depression in older adults.
A comprehensive search was conducted in 4 electronic databases and 1 registered database from inception up to July 2021 to identify relevant trials. The meta-analysis employed Hedge's , along with its 95% CI, and associated and values for the included studies, utilizing Comprehensive Meta-Analysis software.
Qualitative synthesis was performed on 5 eligible studies. Evaluation of methodological quality and bias risk across the papers involved scrutiny of key variables due to the heterogeneous research formats. Our findings indicated a significant moderating effect of MBCT against current depressive symptoms in older adults ( = 0.53, 95% Confidence Intervals (CI) = 0.31-0.75) and a similar effect size for anxiety ( = 0.43, 95% CI = 0.20-0.65). However, caution is warranted due to the limited number of studies and potential publication bias. Further extensive research with longer follow-up measures and larger sample sizes is essential.
This study underscores the effectiveness of MBCT as a treatment for anxiety and despair in older individuals. Mindfulness-based cognitive therapy should be recommended for its positive impact on older adults with depression, and the involvement of authorized psychiatric nurses is crucial for conducting successful MBCT interventions. However, caution is warranted due to the limited number of studies and potential publication bias. Further extensive research with longer follow-up measures and larger sample sizes is essential.
本研究旨在评估基于正念的认知疗法(MBCT)对缓解老年人抑郁症的疗效。
从数据库建立至2021年7月,在4个电子数据库和1个注册数据库中进行全面检索,以识别相关试验。采用综合Meta分析软件,对纳入研究运用Hedge's 及其95%置信区间(CI)以及相关的 和 值进行Meta分析。
对5项符合条件的研究进行了定性综合分析。由于研究形式的异质性,对各论文的方法学质量和偏倚风险评估涉及关键变量的审查。我们的研究结果表明,MBCT对老年人当前的抑郁症状有显著的调节作用( = 0.53,95%置信区间(CI)= 0.31 - 0.75),对焦虑的效应大小相似( = 0.43,95% CI = 0.20 - 0.65)。然而,由于研究数量有限和潜在的发表偏倚,需谨慎对待。进一步开展具有更长随访措施和更大样本量的广泛研究至关重要。
本研究强调了MBCT作为治疗老年人焦虑和绝望的有效性。基于正念的认知疗法因其对抑郁症老年人的积极影响而应被推荐,且授权精神科护士的参与对于成功开展MBCT干预至关重要。然而,由于研究数量有限和潜在的发表偏倚,需谨慎对待。进一步开展具有更长随访措施和更大样本量的广泛研究至关重要。