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胃癌患者围手术期症状群的变化:一项纵向研究。

The change of symptom clusters in gastric cancer patients during the perioperative period: a longitudinal study.

机构信息

Department of Pancreatic and Gastric Surgery, National Cancer Center / National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

出版信息

Support Care Cancer. 2024 May 27;32(6):387. doi: 10.1007/s00520-024-08587-z.

Abstract

AIM AND OBJECTIVES

The purpose of this study was to describe the number, type and trajectory of symptom clusters during the perioperative period in patients with gastric cancer at four different time points. The study also aimed to identify the changes and consistency of these symptom clusters over time.

DESIGN

This was a longitudinal study.

METHODS

This study was conducted in a tertiary cancer hospital with 205 patients with gastric cancer. The M.D. Anderson Symptom Inventory Gastrointestinal Cancer Module was used to assess the incidence and severity of symptom clusters. Exploratory factor analysis was used to extract symptom clusters.

RESULTS

The study identified four symptom clusters in patients with gastric cancer during the perioperative period: gastrointestinal symptom cluster, physical symptom cluster, psychological symptom cluster, and sleep disturbance symptom cluster. These clusters were observed across two to four time points.

CONCLUSION

The findings of this study provide scientific evidence for medical staff and researchers to better understand the symptoms of patients with gastrointestinal cancer during the perioperative period. These findings can help develop individualized interventions for managing symptoms.

RELEVANCE TO CLINICAL PRACTICE

Gastric cancer patients suffered from various symptom clusters, which lasted from one day before surgery to one month after surgery. They should be given careful consideration by clinical staff.

摘要

目的和目标

本研究旨在描述胃癌患者在围手术期四个不同时间点的症状群数量、类型和轨迹。本研究还旨在确定这些症状群随时间的变化和一致性。

设计

这是一项纵向研究。

方法

本研究在一家三级癌症医院进行,共有 205 名胃癌患者。采用 MD 安德森症状清单胃肠道癌模块评估症状群的发生率和严重程度。采用探索性因子分析提取症状群。

结果

本研究在胃癌患者围手术期发现了四个症状群:胃肠道症状群、身体症状群、心理症状群和睡眠障碍症状群。这些群在两个到四个时间点都有观察到。

结论

本研究的结果为医护人员和研究人员提供了科学证据,以更好地了解胃肠道癌症患者围手术期的症状。这些发现有助于制定针对症状的个体化干预措施。

临床相关性

胃癌患者患有各种症状群,从手术前一天持续到手术后一个月。临床工作人员应予以关注。

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