Duke University.
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
Oncol Nurs Forum. 2020 Mar 1;47(2):187-202. doi: 10.1188/20.ONF.187-202.
Patients with gastric cancer experience multiple disease- and treatment-related symptoms. The purpose of this review was to describe the common and co-occurring symptoms experienced by patients with gastric cancer.
Search terms, such as gastric cancer, symptoms, and experience, were used to search PubMed®, CINAHL®, and PsycINFO® for empirical papers published from January 1990 to July 2019.
The search yielded 1,259 articles; 25 studies (21 observational and 4 interventional) were included in this review. Each study was systematically evaluated.
The most common symptoms were categorized into physical and affective/cognitive domains. Three to 17 (median = 7) symptoms occurred concurrently. The severity of most symptoms was reported as mild to moderate. However, patients experienced varying levels of symptom severity following treatment trajectories. Older age, female gender, advanced cancer stage, low socioeconomic status, and total gastrectomy were associated with a greater number and severity of symptoms.
Future research of symptom clusters may clarify the phenotypes and relationship between multiple co-occurring symptoms in patients with gastric cancer to develop targeted interventions that support symptom self-management for this population.
胃癌患者会经历多种与疾病和治疗相关的症状。本综述的目的是描述胃癌患者常见的和同时发生的症状。
使用“gastric cancer”（胃癌）、“symptoms”（症状）和“experience”（体验）等搜索词，在 PubMed®、CINAHL® 和 PsycINFO® 中搜索了 1990 年 1 月至 2019 年 7 月发表的实证论文。
搜索结果产生了 1259 篇文章；纳入了 25 项研究（21 项观察性研究和 4 项干预性研究）。对每项研究都进行了系统评估。
最常见的症状分为身体和情感/认知两个领域。有 3 到 17 个（中位数=7）症状同时出现。大多数症状的严重程度报告为轻度至中度。然而，患者在治疗过程中经历了不同程度的症状严重程度。年龄较大、女性、晚期癌症、低社会经济地位和全胃切除术与更多和更严重的症状有关。
对症状群的未来研究可能会阐明胃癌患者多种同时发生的症状的表型和关系，从而为这一人群开发支持症状自我管理的针对性干预措施。
