Smith E M
J Natl Cancer Inst. 1979 Nov;63(5):1189-98.
Recent literature on morbidity and mortality patterns, known risk factors, and related sociobehavioral characteristics of oral cancer have been examined. Despite variation in populations and methodologies, alcohol and tobacco were seen as the major independent etiologic agents; these effects were associated with age, sex, and religion-ethnicity. Other factors were suggested, but their correlation was less consistent: geographic location, race, socioeconomic status, nutrition, dental conditions, and concurrent diseases. Social and behavioral components may alter risk, stage of disease at diagnosis, treatment or survival from oral cancer. The impact of sociobehavioral elements on the reduction of the incidence of and the mortality from the disease is an important area needing further investigation.
近期有关口腔癌发病率和死亡率模式、已知风险因素以及相关社会行为特征的文献已被研究。尽管不同人群和方法存在差异，但酒精和烟草被视为主要的独立病因；这些影响与年龄、性别和宗教种族有关。还提出了其他因素，但其相关性不太一致：地理位置、种族、社会经济地位、营养、牙齿状况和并发疾病。社会和行为因素可能会改变患口腔癌的风险、诊断时的疾病阶段、治疗或生存率。社会行为因素对降低该疾病发病率和死亡率的影响是一个需要进一步研究的重要领域。
