痘病毒中具有潜在抗病毒活性的生物化合物概述。
The Overview of Potential Antiviral Bioactive Compounds in Poxviruses.
机构信息
Department of Chemistry, Sant Kavi Baba Baijnath Government P.G. College Harakh, Barabanki (UP), 225121, India.
Dr. Rammanohar Lohia Avadh University, Ayodhya, Uttar Pradesh, 224001, India.
出版信息
Adv Exp Med Biol. 2024;1451:331-336. doi: 10.1007/978-3-031-57165-7_21.
Poxviruses belong to the family of double-stranded DNA viruses, and it is pathogenic for humans and spread worldwide. These viruses cause infections and various diseases in human. So, it is required to develop new drugs for the treatment of smallpox or other poxvirus infections. Very few potential compounds for the treatment of poxvirus such as smallpox, chickenpox, and monkeypox have been reported. Most of the compounds has used as vaccines. Cidofovir is most commonly used as a vaccine for the treatment of poxviruses. There are no phytochemicals reported for the treatment of poxviruses. Very few phytochemicals are under investigation for the treatment of poxviruses.
痘病毒属于双链 DNA 病毒家族，对人类具有致病性，并在全球范围内传播。这些病毒会导致人类感染和各种疾病。因此，需要开发新的药物来治疗天花或其他痘病毒感染。目前仅有少数几种用于治疗天花、水痘和猴痘等痘病毒的潜在化合物被报道。其中大部分化合物已被用作疫苗。西多福韦是最常用于治疗痘病毒的疫苗之一。目前尚未有用于治疗痘病毒的植物化学物质被报道。只有少数几种植物化学物质正在被用于治疗痘病毒的研究中。
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