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1990年至2019年中国职业性肺癌疾病负担分析

[An analysis of disease burden of occupational lung cancer in China from 1990 to 2019].

作者信息

Ma H J, Huang S X, Zeng N

机构信息

Department of Respiratory, Tianjin Fifth Central Hospital, Tianjin 300450, China.

出版信息

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2024 May 20;42(5):355-359. doi: 10.3760/cma.j.cn121094-20220623-00338.

Abstract

To analyze the trend of disease burden, including mortality and disability-adjusted life years (DALYs) , of occupational lung cancer in China from 1990 to 2019. In June 2022, the data of occupational lung cancer was obtained from Global Burden of Disease Study 2019 (GBD) . Excel summarized the data, and the mortality rate, DALYs and age-normalized rate were analyzed. Applying Joinpoint Regression Program software annual Percentage Change (APC) and Average Annual Percentage Change Rate (AAPC) . Age-standardized mortality rates ranged from 2.41 in 1990 to 3.14 per 100 000 in 2019, with gender differences and a positive correlation with age. DALYs increased from 580, 000 person-years in 1990 to 1 509 900 person-years in 2019. The rate of standardized DALYs increased from 63.03 per 100 000 in 1990 to 71.65 per 100 000 in 2019. According to the annual percentage change (APC) analysis by Joinpoint Regression Program software, the age-normalized mortality and DALY rates decreased from 2011 to 2016, and the increasing trend from 2016 to 2019 was significantly lower than that before 2011. And the increase at this stage was not statistically significant. The APCC values of mortality rate, standardized mortality rate, DALYs rate and changed DALYs rate were 3.28, 0.92, 2.64 and 0.44, respectively, and the trend differences were statistically significant. The disease burden of occupational lung cancer is increasing from 1990 to 2019. Lung cancer screening should be carried out among high-risk populations to achieve early diagnosis and treatment.

摘要

分析1990年至2019年中国职业性肺癌的疾病负担趋势,包括死亡率和伤残调整生命年(DALYs)。2022年6月,从《2019年全球疾病负担研究》(GBD)中获取职业性肺癌数据。用Excel汇总数据,并分析死亡率、伤残调整生命年和年龄标准化率。应用Joinpoint回归程序软件计算年度百分比变化(APC)和平均年度百分比变化率(AAPC)。年龄标准化死亡率从1990年的每10万人2.41例增至2019年的每10万人3.14例,存在性别差异且与年龄呈正相关。伤残调整生命年从1990年的580000人年增至2019年的1509900人年。标准化伤残调整生命年率从1990年的每10万人63.03例增至2019年的每10万人71.65例。根据Joinpoint回归程序软件的年度百分比变化(APC)分析,年龄标准化死亡率和伤残调整生命年率在2011年至2016年下降,2016年至2019年的上升趋势显著低于2011年之前,且该阶段的上升无统计学意义。死亡率、标准化死亡率、伤残调整生命年率和变化的伤残调整生命年率的APC值分别为3.28、0.92、2.64和0.44,趋势差异有统计学意义。1990年至2019年职业性肺癌的疾病负担在增加。应在高危人群中开展肺癌筛查以实现早期诊断和治疗。

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