盐酸毛果芸香碱聚乳酸微胶囊的体内评价
The in vivo evaluation of poly(lactic acid) microcapsules of pilocarpine hydrochloride.
作者信息
Vidmar V, Pepeljnjak S, Jalsenjak I
机构信息
Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia, Yugoslavia.
出版信息
J Microencapsul. 1985 Oct-Dec;2(4):289-92. doi: 10.3109/02652048509033840.
PMID:3880490
Abstract
Poly(lactic acid) microcapsules of pilocarpine hydrochloride were prepared and evaluated by measuring a miotic effect in rabbits. The microcapsule suspension showed prolongation of miosis and an improved bioavailability when compared with a standard eye dosage form.
摘要
制备了盐酸毛果芸香碱的聚乳酸微胶囊，并通过测量家兔的缩瞳效应进行评估。与标准眼用剂型相比，微胶囊悬浮液显示出缩瞳作用的延长和生物利用度的提高。
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