Internal Medicine Department, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Kermanshah University of Medical Sciences, Kermanshah, Iran.
BMC Endocr Disord. 2024 May 29;24(1):75. doi: 10.1186/s12902-024-01611-7.
Metabolic syndrome (MetS) is associated to sleep duration. It is crucial to identify factors that disrupt sleep regulation. The study aimed to assess the indirect effect of risk factors related to MetS severity through sleep duration by utilizing a structural equation model (SEM).
The study involving 3,935 adults from the baseline data of the Ravansar Non-Communicable Disease (RaNCD) cohort study. MetS severity scores were the outcome variables. SEM was employed to explore the relationships, utilizing IBM SPSS and AMOS version 23.
The mean MetS severity score was higher in women compared to men (0.25 vs. 0.16, P = 0.003). In men, socioeconomic status (SES) has a positive direct effect (β = 0.048) and a negative indirect effect (β=-0.006) on MetS severity. Increased physical activity is directly (β=-0.036) and indirectly (β=-0.093) associated with reducing MetS severity. Nap duration is directly linked to an increase (β = 0.072) but has an indirect effect (β=-0.008) in decreasing MetS severity. In women, SES has a direct (β=-0.020) and indirect (β=-0.001) inverse relationship with MetS severity. Increased physical activity is directly (β=-0.048) and indirectly (β=-0.036) associated with decreasing MetS severity in women. Nap duration is directly associated with an increase in MetS severity (β=-0.018) but indirectly contributes to its reduction (β=-0.002). Sleep duration not only directly affects MetS severity but is also influenced by age, SES, physical activity, obesity and nap duration.
Physical activity, SES, and nap duration directly and indirectly effect the MetS severity. Sleep duration was recognized as a mediating variable that supports the indirect effects.
代谢综合征（MetS）与睡眠时间有关。识别扰乱睡眠调节的因素至关重要。本研究旨在通过结构方程模型（SEM）评估与 MetS 严重程度相关的危险因素通过睡眠时间的间接影响。
这项研究涉及 Ravansar 非传染性疾病（RaNCD）队列研究的基线数据中的 3935 名成年人。MetS 严重程度评分是结果变量。使用 IBM SPSS 和 AMOS 版本 23 利用 SEM 探讨了这些关系。
女性的平均 MetS 严重程度评分高于男性（0.25 对 0.16，P=0.003）。在男性中，社会经济地位（SES）对 MetS 严重程度有正向直接影响（β=0.048）和负向间接影响（β=-0.006）。增加体力活动直接（β=-0.036）和间接（β=-0.093）与降低 MetS 严重程度相关。午睡时间与 MetS 严重程度的增加直接相关（β=0.072），但具有间接影响（β=-0.008）。在女性中，SES 与 MetS 严重程度有直接（β=-0.020）和间接（β=-0.001）负相关。增加体力活动与女性 MetS 严重程度的降低直接相关（β=-0.048）和间接相关（β=-0.036）。午睡时间与 MetS 严重程度直接相关（β=-0.018），但间接有助于降低 MetS 严重程度（β=-0.002）。睡眠持续时间不仅直接影响 MetS 严重程度，而且还受到年龄、SES、体力活动、肥胖和午睡时间的影响。
体力活动、SES 和午睡时间直接和间接影响 MetS 严重程度。睡眠持续时间被认为是支持间接影响的中介变量。
