Department of Health Management Center, Clinical Medical College and Affiliated Hospital of Chengdu University, Chengdu University, Sichuan Province, Jinniu District, Chengdu City, 610081, China.
China Railway Chengdu Group Co., Ltd., Jinniu District, Chengdu City, 610081, Sichuan Province, China.
BMC Cardiovasc Disord. 2022 Jun 11;22(1):263. doi: 10.1186/s12872-022-02705-7.
Metabolic syndrome (MetS) increases the risk of new diabetes and cardiovascular disease. Night shift work (NSW) may influence metabolic disturbance and lead to MetS. This study aims to investigate the association between long-term NSW (≥ 10 years) and MetS combined with its components in male railway workers in southwest China.
11,023 male railway workers with long-term NSW of more than 10 years in the Physical Examination Center of the Affiliated Hospital of Chengdu University were enrolled. The basic data were collected by investigators and blood test results were collected. The primary outcome was the prevalence of metabolic syndrome. The results were analyzed using statistical software SPSS 22.0.
In total, 11,023 people over the age of 40 with more than 10 years of working experience were enrolled, and 4759 (43.2%) participants had a diagnosis of MetS. The basic data indicated that night shift workers tended to be younger, shorter working years, but with higher body mass index and longer hip circumference (p < 0.05). The adjusted analysis revealed that there was no significant association between NSW and metabolic syndrome (OR 1.03, 95% CI 0.94-1.12, p = 0.543). NSW was associated with SBP ≥ 130 mmHg (OR 1.11, 95% CI 1.02-1.21, p < 0.001) and waist circumference ≥ 90 cm (OR 1.11, 95% CI 1.02-1.21, p < 0.001).
Long-term night shift workers had a higher prevalence of MetS. However, long-term NSW is not associated with a significantly increased risk of metabolic syndrome in male railway workers in southwest China. Long-term NSW is associated with elevated SBP, and waist circumference increase.
代谢综合征（MetS）会增加新发糖尿病和心血管疾病的风险。夜班工作（NSW）可能会影响代谢紊乱，导致 MetS。本研究旨在探讨中国西南部长期 NSW（≥10 年）与代谢综合征及其成分的关系。
纳入成都大学附属医院体检中心 11023 名 NSW 时间超过 10 年的男性铁路工人。调查员收集基本数据和血液检测结果。主要结局为代谢综合征的患病率。使用统计软件 SPSS 22.0 分析结果。
共纳入 11023 名年龄超过 40 岁、工作经验超过 10 年的人群，其中 4759 人（43.2%）被诊断为代谢综合征。基础数据显示，夜班工人往往更年轻，工作年限较短，但体重指数和臀围较高（p<0.05）。调整分析显示，NSW 与代谢综合征之间无显著关联（OR 1.03，95%CI 0.94-1.12，p=0.543）。NSW 与 SBP≥130mmHg（OR 1.11，95%CI 1.02-1.21，p<0.001）和腰围≥90cm（OR 1.11，95%CI 1.02-1.21，p<0.001）相关。
长期夜班工人代谢综合征患病率较高。然而，长期 NSW 与中国西南部男性铁路工人代谢综合征的风险增加无关。长期 NSW 与 SBP 升高和腰围增加有关。
