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帕金森病患者的北欧式健走与摆臂不对称性:一项随机临床试验方案

Nordic walking and arm swing asymmetry in people with Parkinson's disease: protocol for a randomised clinical trial.

作者信息

Espinoza-Araneda Jessica, Caparros-Manosalva Cristian, da Cunha Maira, Marzuca-Nassr Gabriel Nasri, Fritz-Silva Nicole, Pagnussat Aline S

机构信息

Faculty of Health Science, Department of Human Movement Sciences, University of Talca, Talca, Chile.

Interuniversity Center for Healthy Aging RED21993, Chile.

出版信息

BMJ Open Sport Exerc Med. 2024 May 27;10(2):e002029. doi: 10.1136/bmjsem-2024-002029. eCollection 2024.

DOI:10.1136/bmjsem-2024-002029
PMID:38808265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11131108/
Abstract

People with Parkinson's disease (PD) face disruptions in arm swing (AS) motion during walking, including a reduction in amplitude and an increase in asymmetry. Both conditions are detrimental to gait performance. Nordic walking (NW) is a walking modality that uses poles and can positively affect the parameters of AS. This study aims to compare an NW with a free walking (FW) protocol and investigate its effects on AS asymmetry, AS amplitude and gait parameters in people with PD. Twenty-eight people with PD, stages 1-3 on the Hoehn and Yahr Scale, will be randomly assigned to the NW training group (n=14) or the FW training group (n=14). The primary outcomes are amplitude asymmetry of AS (%) and AS amplitude (deg). We will also analyse temporospatial measurements during walking, functional mobility and quality of life. Blinded researchers will conduct evaluations at baseline (T0), postintervention (T1) and at 1 month follow-up (T2). Participants will complete 24 supervised NW or FW training sessions for 12 weeks. This is the first study to address the effects of NW on the asymmetry of AS, AS amplitude and its influence on gait parameters. We hypothesise that an NW programme in PD will reduce the asymmetry and increase the AS amplitude during gait to a greater extent than FW. The results of this study may provide new evidence to understand the effects of NW on gait in people with PD. The study was registered in ClinicalTrial.gov (NCT06342271).

摘要

帕金森病(PD)患者在行走过程中会出现摆臂(AS)运动紊乱,包括幅度减小和不对称性增加。这两种情况都会对步态表现产生不利影响。北欧健走(NW)是一种使用手杖的行走方式,可对AS参数产生积极影响。本研究旨在比较NW与自由行走(FW)方案,并研究其对PD患者AS不对称性、AS幅度和步态参数的影响。28名Hoehn和Yahr量表1-3期的PD患者将被随机分配到NW训练组(n=14)或FW训练组(n=14)。主要结局指标为AS的幅度不对称性(%)和AS幅度(度)。我们还将分析行走过程中的时空测量、功能活动能力和生活质量。盲法研究人员将在基线(T0)、干预后(T1)和1个月随访(T2)时进行评估。参与者将在12周内完成24次由专人指导的NW或FW训练课程。这是第一项研究NW对AS不对称性、AS幅度及其对步态参数影响的研究。我们假设,与FW相比,PD患者的NW方案在步态期间将更大程度地减少不对称性并增加AS幅度。本研究结果可能为理解NW对PD患者步态的影响提供新的证据。该研究已在ClinicalTrial.gov(NCT06342271)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3af/11131108/886985dcb30e/bmjsem-2024-002029f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3af/11131108/886985dcb30e/bmjsem-2024-002029f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3af/11131108/886985dcb30e/bmjsem-2024-002029f01.jpg

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本文引用的文献

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Nordic Walking and Free Walking Improve the Quality of Life, Cognitive Function, and Depressive Symptoms in Individuals with Parkinson's Disease: A Randomized Clinical Trial.北欧式健走和自由行走改善帕金森病患者的生活质量、认知功能和抑郁症状:一项随机临床试验。
J Funct Morphol Kinesiol. 2020 Nov 10;5(4):82. doi: 10.3390/jfmk5040082.
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Sci Rep. 2021 Jan 12;11(1):752. doi: 10.1038/s41598-020-80768-2.
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Quality of life in Parkinson's disease: A systematic review and meta-analysis of comparative studies.帕金森病患者的生活质量:一项比较研究的系统评价和荟萃分析。
CNS Neurosci Ther. 2021 Mar;27(3):270-279. doi: 10.1111/cns.13549. Epub 2020 Dec 28.
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Restricted Arm Swing in People With Parkinson's Disease Decreases Step Length and Time on Destabilizing Surfaces.帕金森病患者受限的摆臂会缩短在不稳定表面上行走的步长并减少行走时间。
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Quantification of Arm Swing during Walking in Healthy Adults and Parkinson's Disease Patients: Wearable Sensor-Based Algorithm Development and Validation.健康成年人和帕金森病患者行走时手臂摆动的定量分析:基于可穿戴传感器的算法开发和验证。
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Effectiveness of 6-Week Nordic Walking Training on Functional Performance, Gait Quality, and Quality of Life in Parkinson's Disease.6 周北欧健走训练对帕金森病患者功能表现、步态质量和生活质量的影响。
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