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焦虑症状与 6 年血压变化及高血压发病的相关性:来自西班牙裔社区健康研究/拉丁裔研究的结果。

Associations of Anxiety Symptoms With 6-Year Blood Pressure Changes and Incident Hypertension: Results From the Hispanic Community Health Study/Study of Latinos.

机构信息

Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California, USA.

South Bay Latino Research Center, San Diego State University, Chula Vista, California, USA.

出版信息

Ann Behav Med. 2024 Jun 18;58(7):488-497. doi: 10.1093/abm/kaae026.

Abstract

BACKGROUND

Despite the high burden of anxiety and hypertension in Hispanic/Latino adults, little is known about their association in this population.

PURPOSE

To examine the associations of anxiety symptoms with 6-year changes in blood pressure (BP) and incident hypertension in Hispanic/Latino adults.

METHODS

We examined data from a probability sample of 10,881 Hispanic/Latino persons aged 18-74 who attended visits 1 (V1; 2008-2011) and 2 (V2; 2014-2017) of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a prospective cohort study. Anxiety symptoms were assessed at V1 using the 10-item Spielberger Trait Anxiety Scale (M = 17.1; Range = 10-40) and dichotomized using a cut-point of 20, the highest quartile in this cohort. BP was measured at both visits using a standardized protocol.

RESULTS

Adults with elevated anxiety symptoms had a 1.02 mm Hg greater increase in systolic (p = .02) and a 0.75 mm Hg greater increase in diastolic BP (p = .02) over 6.1 years than those with lower symptoms, after adjusting for sociodemographic and clinical covariates. These associations differed by sex. Elevated anxiety was associated with a greater increase in systolic and diastolic BP in men only. Among persons without hypertension at V1 (N = 7,412), those with elevated anxiety symptoms at V1 had a 22% higher incidence of hypertension (p = .02) 6.1 years later.

CONCLUSIONS

Our findings underscore the importance of screening for and treating elevated anxiety symptoms to help prevent hypertension. Further research on the role of sex and underlying mechanisms is warranted.

摘要

背景

尽管西班牙裔/拉丁裔成年人的焦虑和高血压负担很高,但对于这一人群中焦虑与高血压的关系知之甚少。

目的

探讨西班牙裔/拉丁裔成年人焦虑症状与 6 年内血压(BP)变化和高血压发病的关系。

方法

我们分析了参加西班牙裔社区健康研究/拉丁裔研究(HCHS/SOL)的 10881 名 18-74 岁西班牙裔/拉丁裔个体的概率样本数据,这些个体参加了 HCHS/SOL 的第 1 次(V1;2008-2011 年)和第 2 次(V2;2014-2017 年)就诊。采用 10 项斯皮尔伯格特质焦虑量表(M=17.1;范围 10-40)在 V1 评估焦虑症状,并使用该队列的最高四分位数(20)作为切点将其分为高低两组。两次就诊均采用标准化方案测量血压。

结果

在调整社会人口学和临床协变量后,与低症状者相比,焦虑症状升高的成年人在 6.1 年内收缩压(p=0.02)升高 1.02mmHg,舒张压(p=0.02)升高 0.75mmHg。这些关联在性别上存在差异。仅在男性中,焦虑升高与收缩压和舒张压的增加更为相关。在 V1 时无高血压的人群中(N=7412),V1 时焦虑症状升高者在 6.1 年后高血压的发病率增加 22%(p=0.02)。

结论

我们的研究结果强调了筛查和治疗焦虑症状升高以预防高血压的重要性。需要进一步研究性别和潜在机制的作用。

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