Korsten M A, Lieber C S
Med Clin North Am. 1979 Sep;63(5):963-72. doi: 10.1016/s0025-7125(16)31653-4.
Effective management of nutritional problems in the alcoholic patient requires that the clinician understand the complex interaction of alcohol and nutrition. Nutritional deficiencies should be prevented and, if present, corrected. However, experimental, clinical, and epidemiological evidence indicates that despite adequate diets, ethanol has direct toxic effects on the digestion, absorption and activation of foodstuff. Furthermore, recent studies have shown that even in well nourished populations relatively small amounts of alcohol may have cirrhogenic potential. For these reasons, the overall approach to the management of the alcoholic must involve the control of alcohol intake as well as the prevention and correction of nutritional disturbances.
有效管理酒精依赖患者的营养问题,要求临床医生了解酒精与营养之间复杂的相互作用。应预防营养缺乏,若已出现则加以纠正。然而,实验、临床和流行病学证据表明,尽管饮食充足,但乙醇对食物的消化、吸收和活化具有直接毒性作用。此外,最近的研究表明,即使在营养良好的人群中,相对少量的酒精也可能具有致肝硬化的潜力。基于这些原因,对酒精依赖者的总体管理方法必须包括控制酒精摄入量以及预防和纠正营养紊乱。