Lanfranchi Filippo, Mancino Laura, Foltran Gabriele, Nicole' Lorenzo, Michieletto Lucio
Respiratory Disease Unit, Department of Cardiac Thiraciuc and Vascular Sciences, Ospedale dell'Angelo, Venice, Italy.
Pathology Unit, Ospedale dell'Angelo, Venice, Italy.
Front Oncol. 2024 May 15;14:1394022. doi: 10.3389/fonc.2024.1394022. eCollection 2024.
Diagnosis of peripheral pulmonary lesions (PPL) is one of the most challenging fields in early lung cancer diagnosis. Despite novel techniques and new approaches to the periphery of the lung, almost 25% of PPL remains undiagnosed. Virtual bronchoscopy navigation (VBN) potentially allows to sample PPL previously not reachable with conventional bronchoscopy. In this preliminary report, we described nine cases of PPL (in which conventional bronchoscopy did not reach the lesion) sampled with VBN, from which we obtained a diagnosis in seven out of nine cases (77.8%), consistent with other reported results in literature. More large-scale data are needed to whether VBN can increase diagnostic yield (DY) of PPL.
外周肺病变（PPL）的诊断是早期肺癌诊断中最具挑战性的领域之一。尽管有针对肺外周的新技术和新方法，但仍有近25%的PPL无法确诊。虚拟支气管镜导航（VBN）有可能对传统支气管镜先前无法触及的PPL进行采样。在这份初步报告中，我们描述了9例通过VBN采样的PPL（传统支气管镜未触及病变），其中9例中有7例（77.8%）得到确诊，这与文献中其他报道的结果一致。还需要更多大规模数据来确定VBN是否能提高PPL的诊断率（DY）。
