Mardirossian G, Cooper S A
J Oral Maxillofac Surg. 1985 Feb;43(2):106-9. doi: 10.1016/0278-2391(85)90056-4.
The analgesic efficacy of flurbiprofen 25 mg and 50 mg compared with aspirin 650 mg and placebo (lactose) was evaluated. Subjects were 164 dental outpatients undergoing the surgical removal of impacted teeth. Each subject received a single dose of study medication and was evaluated hourly for six hours. Aspirin was superior to placebo in all measures of analgesic efficacy, and both dosages of flurbiprofen were superior to aspirin.
评估了25毫克和50毫克氟比洛芬与650毫克阿司匹林及安慰剂(乳糖)相比的镇痛效果。受试者为164名接受阻生齿外科拔除术的牙科门诊患者。每位受试者接受一剂研究药物,并在6小时内每小时进行一次评估。在所有镇痛效果指标上,阿司匹林均优于安慰剂,且两种剂量的氟比洛芬均优于阿司匹林。