Suppr超能文献

瘘管滴注法在肠-气瘘营养管理中的有效性:巴拿马圣托马斯医院的一项回顾性研究

Effectiveness of Fistuloclysis in Nutritional Management of Enteroatmospheric Fistulas: A Retrospective Study at Santo Tomás Hospital, Panama.

作者信息

Valderrama Otilda M, Quiodettis Martha A, Monteza Stephanie

机构信息

Trauma Unit, Hospital Santo Tomás, Panama City, PAN.

出版信息

Cureus. 2024 Apr 30;16(4):e59403. doi: 10.7759/cureus.59403. eCollection 2024 Apr.

Abstract

Introduction Enteroatmospheric fistulas (EAF) present significant challenges in surgical management due to their complex nature and high mortality rate. Traditional approaches often rely on prolonged parenteral nutrition, but emerging evidence suggests the potential benefits of enteral nutrition via fistuloclysis, an underappreciated enteral nutrition route. This study aims to evaluate the effectiveness of nutritional therapy, specifically fistuloclysis, in patients with EAF managed at the Trauma Unit of Santo Tomás Hospital, Panama. Methods A retrospective analysis was conducted on nine male patients diagnosed with EAF between January 2016 and December 2020. Data on demographics, fistula characteristics, and nutritional management were collected through chart review. Descriptive statistics were used for analysis. Results We analyzed nine patients, all of whom received enteral nutrition (EN) via fistuloclysis in a median of 5.5 days from the diagnosis of EAF. Seven patients required parenteral nutrition (PN) at the beginning. The use of specialized enteral formulas, supplemented with hydrolyzed proteins and medium-chain triglycerides, facilitated discontinuation of PN once 80% of nutritional requirements were met via the enteral route, and EN was continued until definitive surgery. The median duration of PN was 34 days. No adverse effects related to EN were observed, whereas complications such as central venous catheter infections were reported in all cases requiring PN. Conclusion Fistuloclysis is a viable and effective alternative to traditional PN in patients with EAF. Specialized nutritional strategies, including the use of semi-elemental formulas, contribute to improved outcomes and reduced complications. Early initiation and gradual increase in enteral nutrition via fistuloclysis demonstrate safety and efficacy, underscoring the importance of tailored nutritional approaches in optimizing patient care for complex surgical conditions.

摘要

引言 肠-大气瘘(EAF)因其复杂的性质和高死亡率,在外科治疗中面临重大挑战。传统方法通常依赖长期肠外营养,但新出现的证据表明,经瘘管滴注进行肠内营养具有潜在益处,这是一种未得到充分重视的肠内营养途径。本研究旨在评估营养治疗,特别是经瘘管滴注,对巴拿马圣托马斯医院创伤科收治的EAF患者的有效性。方法 对2016年1月至2020年12月期间诊断为EAF的9例男性患者进行回顾性分析。通过病历审查收集人口统计学、瘘管特征和营养管理数据。采用描述性统计进行分析。结果 我们分析了9例患者,所有患者在诊断EAF后的中位5.5天开始经瘘管滴注接受肠内营养(EN)。7例患者起初需要肠外营养(PN)。使用添加水解蛋白和中链甘油三酯的特殊肠内配方,一旦通过肠内途径满足80%的营养需求,就有助于停止PN,并继续进行EN直至确定性手术。PN的中位持续时间为34天。未观察到与EN相关的不良反应,而在所有需要PN的病例中均报告了诸如中心静脉导管感染等并发症。结论 对于EAF患者,经瘘管滴注是传统PN的一种可行且有效的替代方法。包括使用半要素配方在内的特殊营养策略有助于改善结局并减少并发症。通过经瘘管滴注早期开始并逐步增加肠内营养显示出安全性和有效性,强调了在优化复杂手术情况的患者护理中采用个性化营养方法的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/912e/11139537/d5bec39d4ceb/cureus-0016-00000059403-i01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验