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产后垂体炎:一例病例报告及文献综述

Postpartum Hypophysitis: A Case Report and a Literature Review.

作者信息

Baral Bidisha, Sharma Monica, Khadka Ranjan, Naveed Ossama, Bekele Ammer

机构信息

Medicine, Saint Agnes Hospital, Baltimore, USA.

Internal Medicine, Saint Agnes Hospital, Baltimore, USA.

出版信息

Cureus. 2024 Apr 30;16(4):e59396. doi: 10.7759/cureus.59396. eCollection 2024 Apr.

DOI:10.7759/cureus.59396
PMID:38817522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11139491/
Abstract

Hypophysitis is a rare pituitary gland disease primarily seen in females of reproductive age. Patients can present with various non-specific symptoms, which makes diagnosis challenging. Appropriate endocrine workup supplemented with magnetic resonance imaging (MRI) helps establish a diagnosis. We present a case of a 22-year-old postpartum female who came with nausea, vomiting, and abdominal pain. Global endocrine insufficiency was seen in the laboratory workup, and an MRI confirmed the diagnosis of hypophysitis. She was treated with steroid and thyroid hormone supplementation.

摘要

垂体炎是一种罕见的垂体疾病,主要见于育龄女性。患者可能出现各种非特异性症状,这使得诊断具有挑战性。适当的内分泌检查辅以磁共振成像(MRI)有助于确诊。我们报告一例22岁产后女性病例,该患者因恶心、呕吐和腹痛前来就诊。实验室检查发现全身性内分泌功能减退,MRI确诊为垂体炎。她接受了类固醇和甲状腺激素补充治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e6/11139491/ed892de3915e/cureus-0016-00000059396-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e6/11139491/ed892de3915e/cureus-0016-00000059396-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85e6/11139491/ed892de3915e/cureus-0016-00000059396-i01.jpg

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本文引用的文献

1
Neuroimaging of hypophysitis: etiologies and imaging mimics.垂体炎的神经影像学:病因和影像模拟。
Jpn J Radiol. 2023 Sep;41(9):911-927. doi: 10.1007/s11604-023-01417-y. Epub 2023 Apr 3.
2
Pregnancy-related hypophysitis revisited.妊娠相关垂体炎再探。
Eur J Endocrinol. 2023 Feb 14;188(2). doi: 10.1093/ejendo/lvad003.
3
Glucocorticoid therapy as first-line treatment in primary hypophysitis: a systematic review and individual patient data meta-analysis.糖皮质激素治疗作为原发性垂体炎的一线治疗:一项系统评价和个体患者数据荟萃分析。
Endocr Connect. 2022 Dec 22;12(2). doi: 10.1530/EC-22-0311. Print 2023 Feb 1.
4
Outcomes of Initial Management Strategies in Patients With Autoimmune Lymphocytic Hypophysitis: A Systematic Review and Meta-analysis.自身免疫性淋巴细胞性垂体炎患者初始治疗策略的结局:系统评价和荟萃分析。
J Clin Endocrinol Metab. 2022 Mar 24;107(4):1170-1190. doi: 10.1210/clinem/dgab839.
5
Hypophysitis, the Growing Spectrum of a Rare Pituitary Disease.垂体炎,一种罕见垂体疾病的不断扩展的范畴。
J Clin Endocrinol Metab. 2022 Jan 1;107(1):10-28. doi: 10.1210/clinem/dgab672.
6
Insights into non-classic and emerging causes of hypopituitarism.对垂体功能减退症的非经典和新兴病因的深入了解。
Nat Rev Endocrinol. 2021 Feb;17(2):114-129. doi: 10.1038/s41574-020-00437-2. Epub 2020 Nov 27.
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Clinical Characteristics of Primary Hypophysitis - A Single-Centre Series of 60 Cases.原发性垂体炎的临床特征 - 单中心 60 例系列研究。
Exp Clin Endocrinol Diabetes. 2021 Mar;129(3):234-240. doi: 10.1055/a-1163-7304. Epub 2020 Aug 7.
8
Clinical Characteristics, Management, and Treatment Outcomes of Primary Hypophysitis: A Monocentric Cohort.原发性垂体炎的临床特征、管理和治疗结局:一项单中心队列研究。
Horm Metab Res. 2020 Apr;52(4):220-227. doi: 10.1055/a-1113-7777. Epub 2020 Apr 8.
9
Clinical Features, Magnetic Resonance Imaging, and Treatment Experience of 20 Patients with Lymphocytic Hypophysitis in a Single Center.单中心 20 例淋巴细胞性垂体炎患者的临床特征、磁共振成像表现和治疗经验。
World Neurosurg. 2019 Jul;127:e22-e29. doi: 10.1016/j.wneu.2019.01.250. Epub 2019 Feb 18.
10
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Clin Chem Lab Med. 2018 Dec 19;57(2):150-164. doi: 10.1515/cclm-2018-0552.