Pramanik Sourav, Islam Abu S M, Ghosh Iti, Ghosh Pradyut
School of Chemical Sciences, Indian Association for the Cultivation of Science Kolkata 700032 India
Chem Sci. 2024 Apr 30;15(21):7824-7847. doi: 10.1039/d4sc00933a. eCollection 2024 May 29.
Liquid-Liquid Extraction (LLE) is a venerable and widely used method for the separation of a targeted solute between two immiscible liquids. In recent years, this method has gained popularity in the supramolecular chemistry community due to the development of various types of synthetic receptors that effectively and selectively bind specific guests in an aqueous medium through different supramolecular interactions. This has eventually led to the development of state-of-the-art extraction technologies for the removal and purification of anions, cations, ion pairs, and small molecules from one liquid phase to another liquid phase, which is an industrially viable method. The focus of this perspective is to furnish a vivid picture of the current understanding of supramolecular interaction-based LLE chemistry. This will not only help to improve separation technology in the chemical, mining, nuclear waste treatment, and medicinal chemistry sectors but is also useful to address the purity issue of the extractable species, which is otherwise difficult. Thus, up-to-date knowledge on this subject will eventually provide opportunities to develop large-scale waste remediation processes and metallurgy applications that can address important real-life problems.
液-液萃取（LLE）是一种历史悠久且广泛应用的方法，用于在两种互不相溶的液体之间分离目标溶质。近年来，由于各种类型合成受体的发展，该方法在超分子化学领域受到了广泛关注。这些合成受体能够通过不同的超分子相互作用，在水相中有效且选择性地结合特定客体。这最终促成了先进萃取技术的发展，可用于将阴离子、阳离子、离子对和小分子从一个液相转移至另一个液相，这是一种具有工业可行性的方法。本文的重点是生动呈现目前对基于超分子相互作用的液-液萃取化学的理解。这不仅有助于改进化学、采矿、核废料处理和药物化学领域的分离技术，还能解决可萃取物种的纯度问题，否则这一问题很难解决。因此，关于这一主题的最新知识最终将为开发大规模废物修复工艺和冶金应用提供机会，从而解决重要的实际问题。
