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诊断Tenon囊下注射类固醇后罕见的眼眶脓肿:一例报告。

Diagnosis of an unusual orbital abscess following sub-Tenon's steroid injection: a case report.

作者信息

Gupta Isha, Moussa Elliott, Motupally Karun, Morris Sharon

机构信息

Department of Ophthalmology, Gold Coast University Hospital, Hospital Blvd, Southport 4215, Queensland, Australia.

Department of Radiology, Gold Coast University Hospital, Hospital Blvd, Southport 4215, Queensland, Australia.

出版信息

J Surg Case Rep. 2024 May 30;2024(5):rjae339. doi: 10.1093/jscr/rjae339. eCollection 2024 May.

DOI:10.1093/jscr/rjae339
PMID:38817784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11138107/
Abstract

Orbital abscesses are caused by infection within or near the orbit and show obvious signs of pain, proptosis and raised inflammatory markers. Diagnosis is based on clinical features and radiological imaging, and requires early antibiotics and often surgical drainage to save vision. Sub-Tenon's injections of triamcinolone acetonide (TA) have caused localized infections in previous reports, which have responded to therapeutic interventions. Here we report a case where a delayed presentation of an orbital abscess secondary to sub-Tenon's TA for persistent post-operative cystoid macular oedema, without obvious signs of infection, rapidly progressed to cause orbital compartment syndrome. Despite treatment, the patient lost complete vision in the affected eye. This case discusses the rare and unusual cause of abscess formation and a diagnostic dilemma.

摘要

眶脓肿由眶内或眶周感染引起,表现出明显的疼痛、眼球突出和炎症指标升高的症状。诊断基于临床特征和影像学检查,需要早期使用抗生素,且常常需要手术引流以挽救视力。既往报道显示,球后注射曲安奈德(TA)可导致局部感染,这些感染对治疗干预有反应。在此,我们报告一例病例,该患者因持续性术后黄斑囊样水肿接受球后TA注射,在无明显感染迹象的情况下,眶脓肿延迟出现,并迅速进展为眶间隔综合征。尽管进行了治疗,患者患眼仍完全失明。本病例讨论了脓肿形成的罕见且不寻常的原因以及诊断难题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/c586cbae14ff/rjae339f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/714a705d176f/rjae339f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/02f1a742a446/rjae339f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/43b83ecfc1b1/rjae339f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/9994e490da67/rjae339f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/c586cbae14ff/rjae339f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/714a705d176f/rjae339f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/02f1a742a446/rjae339f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/43b83ecfc1b1/rjae339f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/9994e490da67/rjae339f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39ff/11138107/c586cbae14ff/rjae339f5.jpg

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本文引用的文献

1
Orbital abscess: 20 years' experience at a tertiary eye care center.眼眶脓肿:在一家三级眼科护理中心的20年经验
Orbit. 2022 Dec;41(6):751-758. doi: 10.1080/01676830.2021.2013901. Epub 2022 Feb 23.
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Fungal abscess after intra-orbital steroid injection: a case report.球内类固醇注射后真菌性脓肿:病例报告。
Orbit. 2022 Oct;41(5):611-615. doi: 10.1080/01676830.2021.1903043. Epub 2021 Mar 26.
3
Orbital abscess caused by Exophiala dermatitidis following posterior subtenon injection of triamcinolone acetonide: a case report and a review of literature related to Exophiala eye infections.
外瓶霉属致眼眶脓肿 1 例报告及相关眼内感染文献复习
BMC Infect Dis. 2020 Aug 3;20(1):566. doi: 10.1186/s12879-020-05294-y.
4
Orbital abscess following posterior subtenon injection of triamcinolone acetonide.曲安奈德后Tenon囊下注射后眶内脓肿
Orbit. 2017 Jun;36(3):135-136. doi: 10.1080/01676830.2017.1279668. Epub 2017 Mar 3.
5
Intraorbital Cystic Lesions: An Imaging Spectrum.眶内囊性病变:影像学表现谱
Curr Probl Diagn Radiol. 2015 Sep-Oct;44(5):437-48. doi: 10.1067/j.cpradiol.2015.03.003. Epub 2015 Mar 17.
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Orbital abscess with unusual features.具有不典型特征的眶脓肿。
Ophthalmic Plast Reconstr Surg. 2009 Nov-Dec;25(6):450-4. doi: 10.1097/IOP.0b013e3181b80b27.
7
Peribulbar fungal abscess and endophthalmitis following posterior subtenon injection of triamcinolone acetonide.曲安奈德球后注射后发生的球周真菌性脓肿和眼内炎。
Acta Ophthalmol. 2009 Feb;87(1):102-4. doi: 10.1111/j.1755-3768.2007.01166.x. Epub 2008 May 27.
8
Acute orbital abscess complicating deep posterior subtenon triamcinolone injection.深部后Tenon囊下注射曲安奈德并发急性眼眶脓肿
Indian J Ophthalmol. 2008 May-Jun;56(3):246-7. doi: 10.4103/0301-4738.40370.
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Triamcinolone acetonide in ocular therapeutics.曲安奈德在眼部治疗中的应用
Surv Ophthalmol. 2007 Sep-Oct;52(5):503-22. doi: 10.1016/j.survophthal.2007.06.004.
10
Frontal mucocele with an accompanying orbital abscess mimicking a fronto-orbital mucocele: case report.伴有眶脓肿的额窦黏液囊肿酷似额眶黏液囊肿:病例报告
BMC Ear Nose Throat Disord. 2006 Apr 18;6:6. doi: 10.1186/1472-6815-6-6.