Wagh Mira Sudam, Goyal Vipul, Chandramohan K, Subhash R, Jayadevan Neelima, Rakesh C A
Department of Surgical Services (Division of Surgical Oncology), Regional Cancer Centre, 5d, Skyline Maple Heights, Chalakuzhy lane, Trivandrum, Kerala 695004 India.
SUT Hospital, Trivandrum, Kerala India.
Indian J Surg Oncol. 2024 May;15(Suppl 2):325-330. doi: 10.1007/s13193-023-01856-z. Epub 2023 Dec 12.
Osteosarcomas occurring in the extraskeletal system are known as extraskeletal osteosarcomas (ESOS). They are rare, highly malignant tumors, associated with poor prognosis Di et al. World J Clin Cases 11(3):662-668 (2023). This is a case report of a gentleman nearing 60s with a liver mass with impending rupture. He underwent resection of the liver mass and was diagnosed to have with ESOS. He underwent a right hepatectomy on an urgent basis. He had an uneventful postoperative recovery. The histopathology report showed a poorly differentiated malignant neoplasm consistent with osteosarcoma. The patient is doing well 75 days after discharge and currently receiving adjuvant chemotherapy with ifosfamide, adriamycin, and cisplatin. We have also done a comprehensive literature review of this rare tumor. It is an elusive disease that is difficult to diagnose radiologically. The treatment includes a combination of surgery and adjuvant treatment.
发生于骨骼外系统的骨肉瘤被称为骨外骨肉瘤（ESOS）。它们是罕见的高度恶性肿瘤，预后较差（Di等人，《世界临床病例杂志》11(3):662 - 668 (2023)）。这是一例报告，患者为一名快60岁的男性，肝脏有一个即将破裂的肿块。他接受了肝脏肿块切除术，被诊断为骨外骨肉瘤。他紧急接受了右肝切除术。术后恢复顺利。组织病理学报告显示为低分化恶性肿瘤，符合骨肉瘤。患者出院75天后情况良好，目前正在接受异环磷酰胺、阿霉素和顺铂的辅助化疗。我们还对这种罕见肿瘤进行了全面的文献综述。它是一种难以通过放射学诊断的隐匿性疾病。治疗包括手术和辅助治疗相结合。
