Govender D, Rughubar K N
Department of Pathology, University of Natal Medical School, Durban, South Africa.
Pathology. 1998 Aug;30(3):323-5. doi: 10.1080/00313029800169556.
We describe a primary osteosarcoma of the liver in a 72 year old man. The man was symptomatic and had suffered abdominal pain and distension for four months before he died. At autopsy a large tumor of the liver with direct extension into adjacent structures was found. There was no evidence of primary tumor or primary bone lesion at any other site. Histologically, the tumor comprised malignant cells producing abundant osteoid arranged in a lace-like pattern. Smaller chondroblastic and fibroblastic components were also present. These findings were in keeping with a diagnosis of primary hepatic osteosarcoma.
我们描述了一名72岁男性的肝脏原发性骨肉瘤。该男性有症状，在去世前四个月一直遭受腹痛和腹胀。尸检时发现肝脏有一个大肿瘤，肿瘤直接蔓延至相邻结构。在其他任何部位均未发现原发性肿瘤或原发性骨病变的证据。组织学上，肿瘤由产生大量呈花边状排列类骨质的恶性细胞组成。还存在较小的软骨母细胞和成纤维细胞成分。这些发现符合原发性肝骨肉瘤的诊断。
