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65 岁及以上急诊科患者的脓毒症 3 小时治疗包依从性与预后。

Sepsis 3-hour bundle compliance and prognosis in emergency department patients aged 65 years or older.

机构信息

Área de Urgencias, Hospital Clínic, Barcelona, España.

出版信息

Emergencias. 2024 Jun;36(3):179-187. doi: 10.55633/s3me/009.2024.

DOI:10.55633/s3me/009.2024
PMID:38818983
Abstract

OBJECTIVES

To analyze 3-hour bundle compliance in for patients aged 65 years or older with sepsis treated in our emergency department (ED) and to explore the association between compliance and mortality.

MATERIAL AND METHODS

Retrospective observational study in patients aged 65 years or older treated in our ED between January 1, 2020 and December 31, 2022. Factors associated with mortality at the end of the episode were also analyzed.

RESULTS

Data for 190 patients were analyzed; 98 (51%) were men. Eighty-five (45%) were aged between 65 and 79 years, and 105 (55%) were aged 80 years or older. Mortality was higher in the patients over 80 years of age (62%) vs 33% of the patients under 80 years of age (P = .001). Overall mean survival time was 38 days (95% CI, 28-48 days). Cox regression analysis showed that 3-hour bundle compliance was associated with longer survival (HR, 0.56; 95% CI, 0.34-0.95; P = .03). Mean survival in patients older than 80 years was 21 days (95% CI, 13-30 days), and 3-hour bundle compliance was associated with longer survival (hazard ratio, 0.51; 95% CI, 0.3-0.9; P = .02).

CONCLUSION

Three-hour sepsis bundle compliance in the ED was associated with longer survival in patients aged 65 years or older.

摘要

目的

分析在我们急诊科治疗的 65 岁及以上脓毒症患者的 3 小时捆绑包依从性,并探讨其与死亡率的关系。

材料和方法

对 2020 年 1 月 1 日至 2022 年 12 月 31 日在我院急诊科治疗的 65 岁及以上患者进行回顾性观察性研究。还分析了与该疾病结束时死亡率相关的因素。

结果

分析了 190 名患者的数据;98 名(51%)为男性。85 名(45%)年龄在 65 至 79 岁之间,105 名(55%)年龄在 80 岁或以上。80 岁以上患者的死亡率较高(62%),而 80 岁以下患者的死亡率为 33%(P =.001)。总体平均存活时间为 38 天(95%CI,28-48 天)。Cox 回归分析显示,3 小时捆绑包依从性与更长的生存时间相关(HR,0.56;95%CI,0.34-0.95;P =.03)。80 岁以上患者的平均存活时间为 21 天(95%CI,13-30 天),3 小时捆绑包依从性与更长的生存时间相关(危险比,0.51;95%CI,0.3-0.9;P =.02)。

结论

ED 中 3 小时脓毒症捆绑包依从性与 65 岁及以上患者的生存时间延长有关。

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