光学相干断层扫描在儿童幼年特发性关节炎患者前房炎症筛查中的应用。
Optical coherence tomography for the screening of anterior chamber inflammation in paediatric patients diagnosed with juvenile idiopathic arthritis.
机构信息
Paediatric Ophthalmology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Spain.
Paediatric Rheumatology Unit, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat; Department of Surgery and Surgical Specializations, Obstetrics and Paediatrics, Universitat de Barcelona, and Grup d'Estudi per Malalties per Disfunció Immune en Pediatria (GEMDIP), Institut de Recerca Sant Joan de Déu (IRSJD), Esplugues de Llobregat, Spain.
出版信息
Clin Exp Rheumatol. 2024 Jul;42(7):1507-1512. doi: 10.55563/clinexprheumatol/t7pn4v. Epub 2024 May 21.
OBJECTIVES
To evaluate the effectiveness of the anterior segment optical coherence tomography (AS-OCT) for the screening of anterior uveitis in children diagnosed with juvenile idiopathic arthritis (JIA).
METHODS
A cross-sectional, observational, non-randomised study was conducted in JIA patients younger than 18 years. All patients underwent anterior segment (AS-OCT) and macular OCT.
RESULTS
A total of 300 eyes of 150 patients diagnosed with JIA were included; 74% were females, and mean age was 11.12 ± 3.51 years old (range 4.13-18.60). In the slit-lamp examination, anterior uveitis was diagnosed in 16 eyes. In the AS-OCT, anterior uveitis was suspected in 27 eyes; cells were detected in 27 eyes and retrokeratic precipitates in 5 eyes. Sensitivity was 0.94 and specificity was 0.96, positive predictive value was 0.59 and negative predictive value was 0.99, and Kappa-Cohen index was 0.71.
CONCLUSIONS
AS-OCT could be considered for the screening of anterior segment uveitis in children diagnosed with JIA.
目的
评估眼前节光学相干断层扫描（AS-OCT）在儿童幼年特发性关节炎（JIA）患者中筛查前葡萄膜炎的有效性。
方法
进行了一项横断面、观察性、非随机研究，纳入了年龄小于 18 岁的 JIA 患者。所有患者均行眼前节（AS-OCT）和黄斑 OCT 检查。
结果
共纳入 150 例 JIA 患者的 300 只眼；74%为女性，平均年龄为 11.12±3.51 岁（范围为 4.13-18.60）。裂隙灯检查诊断出 16 只眼存在前葡萄膜炎。AS-OCT 检查怀疑 27 只眼存在前葡萄膜炎；27 只眼检测到细胞，5 只眼检测到后弹力层皱褶。敏感性为 0.94，特异性为 0.96，阳性预测值为 0.59，阴性预测值为 0.99，Kappa-Cohen 指数为 0.71。
结论
AS-OCT 可用于筛查诊断为 JIA 的儿童的前节葡萄膜炎。
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