Annuzzi G, Vaccaro O, Caprio S, Di Bonito P, Caso P, Riccardi G, Rivellese A
Clin Physiol. 1985 Feb;5(1):63-70. doi: 10.1111/j.1475-097x.1985.tb00747.x.
The aim of this study was to evaluate whether a relationship exists between impaired glucose tolerance and both habitual physical activity and physical working capacity. Sixty-five apparently healthy subjects with impaired glucose tolerance (according to criteria of the European Association for the Study of Diabetes), age range 40-59 years, and 125 subjects with normal tolerance, sex, age and body mass index matched, were selected among the participants in a health examination survey. They filled in a questionnaire on daily physical activity during work and leisure time and performed an exercise test on a cyclergometer. No difference in physical activity at work was recorded between the groups, but the proportion of individuals who were physically active during leisure time, was significantly lower among the subjects with impaired glucose tolerance (8.1% vs 19.7%; P less than 0.05). Moreover these subjects had a higher heart rate during and 1 min after the standard exercise test (113.4 +/- 15.8 vs 105.7 +/- 17.7 beats/min, P less than 0.005; mean +/- SD). This supports the hypothesis that low physical activity is a risk factor for impaired glucose tolerance, independent of mutual effect of obesity.
本研究的目的是评估糖耐量受损与习惯性体力活动和体力工作能力之间是否存在关联。在一项健康检查调查的参与者中，选取了65名糖耐量受损的明显健康受试者（根据欧洲糖尿病研究协会的标准），年龄在40 - 59岁之间，以及125名糖耐量正常、性别、年龄和体重指数相匹配的受试者。他们填写了一份关于工作和休闲时间日常体力活动的问卷，并在自行车测力计上进行了运动测试。两组之间工作时的体力活动没有差异，但在休闲时间进行体力活动的个体比例，在糖耐量受损的受试者中显著较低（8.1%对19.7%；P小于0.05）。此外，这些受试者在标准运动测试期间及测试后1分钟的心率较高（113.4±15.8对105.7±17.7次/分钟，P小于0.005；平均值±标准差）。这支持了以下假设，即低体力活动是糖耐量受损的一个危险因素，独立于肥胖的相互作用。
