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[肝脏与排卵抑制剂。含雌激素 - 孕激素的甾体口服避孕药对肝功能的影响]

[Liver and ovulation inhibitors. Effects on liver function of estrogen-progestagen containing steroid oral contraceptives].

作者信息

Eisenburg J, Kruis W, Weinzierl M, Scherer U

出版信息

Naturwissenschaften. 1979 Oct;66(10):489-97. doi: 10.1007/BF00404858.

DOI:10.1007/BF00404858
PMID:388238
Abstract

Since introduction of oral contraceptive steroids a variety of physiologic-adaptive and toxic side effects have been reported. -a review is given. The study reports also four cases of hepatic vein thrombosis (Budd-Chiari-Syndrome--Venoocclusive disease) and three cases of benign hepatic tumors (liver cell adenoma and focal nodular hyperplasia) in young women following 2- to 5-year treatment with oral contraceptive steroids.

摘要

自从口服避孕类固醇药物问世以来,已报告了多种生理适应性和毒性副作用。本文对此进行综述。该研究还报告了4例年轻女性在接受2至5年口服避孕类固醇药物治疗后发生肝静脉血栓形成(布-加综合征——肝静脉闭塞病)以及3例良性肝肿瘤(肝细胞腺瘤和局灶性结节性增生)的病例。

相似文献

1
[Liver and ovulation inhibitors. Effects on liver function of estrogen-progestagen containing steroid oral contraceptives].[肝脏与排卵抑制剂。含雌激素 - 孕激素的甾体口服避孕药对肝功能的影响]
Naturwissenschaften. 1979 Oct;66(10):489-97. doi: 10.1007/BF00404858.
2
[Oral contraceptives and blood diseases are the most common causes of Budd-Chiari syndrome].口服避孕药和血液疾病是布加综合征最常见的病因。
Lakartidningen. 1989 Nov 15;86(46):4002-8.
3
Oral contraceptives, pregnancy, and focal nodular hyperplasia of the liver.口服避孕药、妊娠与肝脏局灶性结节性增生
JAMA. 1984 Mar 16;251(11):1461-3.
4
Hepatic complications of oral contraceptive pills and estrogen on MRI: Controversies and update - Adenoma and beyond.口服避孕药和雌激素的肝脏并发症在磁共振成像上的表现:争议与进展——腺瘤及其他。
Magn Reson Imaging. 2019 Jul;60:110-121. doi: 10.1016/j.mri.2019.04.010. Epub 2019 Apr 19.
5
[Oral contraceptives and benign tumorous conditions of the liver (author's transl)].口服避孕药与肝脏良性肿瘤性疾病(作者译)
Radiologe. 1980 Dec;20(12):565-76.
6
[A rare form of benign tumor of the liver possibly related to the use of oral contraceptives: focal pediculated nodular hyperplasia].[一种可能与口服避孕药使用有关的罕见肝脏良性肿瘤:局灶性带蒂结节性增生]
Rev Fr Gynecol Obstet. 1985 Aug-Sep;80(8-9):621-7.
7
Benign hepatic tumors and oral contraceptive pills.良性肝脏肿瘤与口服避孕药
Am J Med. 1976 Dec;61(6):871-7. doi: 10.1016/0002-9343(76)90411-3.
8
[Contraceptives and the liver].[避孕药与肝脏]
Leber Magen Darm. 1981 Sep;11(5):216-26.
9
Hepatic adenoma and focal nodular hyperplasia.肝腺瘤和局灶性结节性增生。
Surg Gynecol Obstet. 1991 Nov;173(5):426-31.
10
Tumorigenic aspects.
Int J Gynaecol Obstet. 1978;16(6):473-8. doi: 10.1002/j.1879-3479.1979.tb00952.x.

本文引用的文献

1
ORAL CONTRACEPTIVES AND LIVER DAMAGE.口服避孕药与肝脏损害
Br Med J. 1964 Oct 31;2(5417):1133.
2
Effectiveness of an oral contraceptive; effects of a progestin-estrogen combination upon fertility, menstrual phenomena, and health.
Science. 1959 Jul 10;130(3367):81-3. doi: 10.1126/science.130.3367.81.
3
Mutual modification of glucose-stimulated serum insulin responses in female rhesus monkeys by ethinyl estradiol and nortestosterone derivatives.乙炔雌二醇和诺睾酮衍生物对雌性恒河猴葡萄糖刺激的血清胰岛素反应的相互调节作用。
J Clin Endocrinol. 1975;41(1):44-53.
4
Estrogen pharmacology. IV. Studies of the structural basis for estrogen-induced impairment of liver function.雌激素药理学。IV。雌激素诱导肝功能损害的结构基础研究。
Medicine (Baltimore). 1966 Nov;45(6):471-9.
5
Budd-Chiari syndrome in women taking oral contraceptives.服用口服避孕药的女性中的布加综合征。
Am J Med. 1971 Jan;50(1):137-40. doi: 10.1016/0002-9343(71)90213-0.
6
Experience with benign tumors of the liver.肝脏良性肿瘤的经验
Surg Gynecol Obstet. 1970 Feb;130(2):285-91.
7
Oral contraceptives and thromboembolic disease. I. Prospective and retrospective studies.
JAMA. 1972 Jan 31;219(5):583-92.
8
Nuclear estrogen receptor of chick liver.鸡肝脏的核雌激素受体。
Biochim Biophys Acta. 1972 Jan 28;261(1):236-44. doi: 10.1016/0304-4165(72)90334-0.
9
Thrombosis of the hepatic veins. "The Budd-Chiari syndrome"--a possible link between oral contraceptives and thrombosis formation.
Am J Gastroenterol. 1966 Jun;45(6):429-43.
10
Liver hamartomas in patients on oral contraceptives.口服避孕药使用者中的肝脏错构瘤。
Br Med J. 1974 Jul 6;3(5922):7-10. doi: 10.1136/bmj.3.5922.7.