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日本人的C6多态性:通过琼脂糖凝胶等电聚焦-免疫固定法分型

C6 polymorphism in Japanese: typing by agarose gel isoelectric focusing-immunofixation.

作者信息

Nishimukai H, Kitamura H, Kishida T, Tamaki Y

出版信息

Hum Hered. 1985;35(1):30-3. doi: 10.1159/000153511.

Abstract

Agarose gel isoelectric focusing was used to investigate the genetic polymorphism of the sixth component of complement (C6) in Japanese. C6 patterns were visualized by the immunofixation procedure. The allele frequencies calculated from 135 individuals were as follows: C6A = 0.467, C6B = 0.481, C6B2 = 0.037, and C6B3 = 0.015. It is suggested that C6*B3 is the fourth common allele characterizing the Japanese population.

摘要

采用琼脂糖凝胶等电聚焦法研究了日本人补体第六成分(C6)的遗传多态性。通过免疫固定程序使C6模式可视化。从135名个体计算出的等位基因频率如下:C6A = 0.467,C6B = 0.481,C6B2 = 0.037,C6B3 = 0.015。提示C6*B3是表征日本人群体的第四常见等位基因。

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