Zhonghua Yi Xue Za Zhi. 2024 Jun 4;104(21):1918-1939. doi: 10.3760/cma.j.cn112137-20240222-00373.
Unruptured intracranial aneurysm (UIA) has an estimated prevalence of about 7% among adults aged 35-75 in China. With the aging population trend, the detection rate of UIA is increasing. Most UIA are incidentally discovered and typically asymptomatic. There has been ongoing debate regarding the choice between aggressive treatment and conservative management. Although UIA has a low annual risk of rupture, once rupture occurs, the mortality and disability rates are high. Based on evidence-based medicine, this clinical management guideline provides 44 recommendations on population screening, clinical imaging diagnosis, risk assessment of growth and rupture, treatment strategies and selection, postoperative follow-up, and management of special populations with UIA. Aiming to provide clinical guidance for clinical doenrs and relevant professionals.
未破裂颅内动脉瘤(UIA)在中国35至75岁成年人中的估计患病率约为7%。随着人口老龄化趋势,UIA的检出率正在上升。大多数UIA是偶然发现的,通常无症状。关于积极治疗和保守管理之间的选择一直存在争议。尽管UIA每年的破裂风险较低,但一旦破裂,死亡率和致残率都很高。基于循证医学,本临床管理指南针对UIA的人群筛查、临床影像诊断、生长和破裂风险评估、治疗策略与选择、术后随访以及特殊人群管理提供了44条建议。旨在为临床医生和相关专业人员提供临床指导。