Université de Sherbrooke, Département de Chimie, 2500 boul. de l'Université, Sherbrooke, J1K 2R1, Canada.
Chem Commun (Camb). 2024 Jun 18;60(50):6419-6422. doi: 10.1039/d4cc01452a.
Simultaneous measurements of various molecules ("multiplex") using electrochemical biosensors typically require multiple electrode implementations, which for neonates, hemophiliacs, is problematic. Here, we introduce the oxazine ATTO 700 into electrochemical aptamer-based biosensors to achieve "true" multiplex, continuous and real-time measurements of two different molecules in undiluted whole blood using a single electrode.
使用电化学生物传感器同时测量多种分子（“多重检测”）通常需要多个电极实现，而对于新生儿和血友病患者来说，这是有问题的。在这里，我们将吖嗪 ATTO 700 引入电化学生物传感器基于适体的生物传感器中，以使用单个电极在未稀释的全血中实现两种不同分子的“真正”多重检测、连续和实时测量。
