College of Clinical Medicine, Fudan University, Shanghai.
School of Nursing, Peking Union Medical College.
J Craniofac Surg. 2024 Jun 1;35(4):e351-e354. doi: 10.1097/SCS.0000000000010077. Epub 2024 Jun 3.
Malignant hyperthermia (MH) is a fatal hyperthermia with a high mortality, which usually occurs during induction of general anesthesia. Dantrolene sodium is a wonder drug currently used for treating malignant hyperthermia. However, preparing, storing, and maintaining dantrolene sodium are crucially expensive, thus making it financially unsatisfactory and difficult for clinicians to acquire in time. Monitoring patients' condition closely and intervening promptly when early signs of malignant hyperthermia occur can effectively prevent the condition from worsening and win over time for the arrival of dantraline sodium. This article is to report a case in which we successfully rescued a child occurring malignant hyperthermia without using dantrolene sodium.
恶性高热(MH)是一种致命的高热,死亡率很高,通常发生在全身麻醉诱导期间。丹曲林钠是目前用于治疗恶性高热的特效药。然而,丹曲林钠的制备、储存和维护费用极高,因此在经济上并不理想,临床医生也很难及时获得。密切监测患者的病情,并在出现恶性高热的早期迹象时及时干预,可以有效地防止病情恶化,并为丹曲林钠的到来赢得时间。本文报告了一例成功救治未使用丹曲林钠的恶性高热患儿的病例。