Ezveci Huriye, Doğru Şükran, Akkuş Fatih, Metin Ülfet Sena, Gezginc Kazim
Necmettin Erbakan University (NEU) Meram Faculty of Medicine, Clinic of obstetric and gynecology Division of maternal and fetal medicine, Konya, Turkey.
Necmettin Erbakan University (NEU) Meram Faculty of Medicine, Clinic of obstetric and gynecology, Konya, Turkey.
Z Geburtshilfe Neonatol. 2024 Dec;228(6):507-513. doi: 10.1055/a-2311-4945. Epub 2024 Jun 3.
This study aims to compare the perinatal outcomes of pregnant women with heart disease and a healthy pregnant control group, as well as the maternal and newborn outcomes of pregnant women with congenital heart disease and acquired heart disease.
Pregnant women with heart disease and healthy control pregnant women were included in this retrospective study. Sociodemographic data of all patients included in the study were obtained from electronic records. Perinatal outcomes of all patients were compared.
A total of 258 pregnant women were included in the study. While 129 pregnant women were diagnosed with heart disease, 129 patients were low-risk pregnant women. Preeclampsia (p=0.004) and cesarean section (p=0.01) rates were higher in pregnant women with heart disease compared to healthy pregnant women. Compared with healthy pregnant women, pregnant women with heart disease had a lower birth weight (p=0.003), a higher fetal growth restriction (FGR) rate (p=0.036), lower birth percentiles (p=0.002), a lower 5-minute APGAR (p=0.0001), a higher neonatal intensive care unit (NICU) admission rate (p=0.001), and a longer NICU stay rate (p=0.001). The mean gestational age at birth of pregnant women with congenital heart disease was higher than that of those with acquired heart disease (p=0.017).
It was observed that all maternal heart diseases were associated with adverse perinatal outcomes compared to healthy pregnant women. In this series, perinatal adverse outcomes of pregnant women with congenital and acquired heart disease did not differ.
本研究旨在比较患有心脏病的孕妇与健康孕妇对照组的围产期结局，以及先天性心脏病孕妇和后天性心脏病孕妇的母婴结局。
本回顾性研究纳入了患有心脏病的孕妇和健康对照孕妇。研究中所有患者的社会人口统计学数据均从电子记录中获取。比较了所有患者的围产期结局。
本研究共纳入258名孕妇。其中129名孕妇被诊断患有心脏病，129名患者为低风险孕妇。与健康孕妇相比，患有心脏病的孕妇子痫前期（p = 0.004）和剖宫产（p = 0.01）发生率更高。与健康孕妇相比，患有心脏病的孕妇出生体重更低（p = 0.003），胎儿生长受限（FGR）发生率更高（p = 0.036），出生百分位数更低（p = 0.002），5分钟阿氏评分更低（p = 0.0001），新生儿重症监护病房（NICU）入院率更高（p = 0.001），以及NICU住院时间更长（p = 0.001）。先天性心脏病孕妇的平均出生孕周高于后天性心脏病孕妇（p = 0.017）。
观察发现，与健康孕妇相比，所有母体心脏病均与不良围产期结局相关。在本系列研究中，先天性和后天性心脏病孕妇的围产期不良结局并无差异。
