Alsuwaidi Salem, Almatrooshi Aisha, Shah Maanas, Hakam Abeer, Tawse-Smith Andrew, Alsabeeha Nabeel H M, Atieh Momen A
Mohammed Bin Rashid University of Medicine and Health Sciences, Hamdan Bin Mohammed College of Dental Medicine, Dubai Health, Dubai, United Arab Emirates.
Dubai Health, Dubai, United Arab Emirates.
J Periodontol. 2024 Nov;95(11):1048-1059. doi: 10.1002/JPER.24-0099. Epub 2024 Jun 3.
The aim of this randomized controlled trial was to assess clinical and patient-reported outcomes of subgingival instrumentation (SI) with adjunctive use of erythritol airflowing (EAF) compared to SI alone in the treatment of periodontitis.
Twenty-six participants with Stage III/IV periodontitis requiring nonsurgical periodontal treatment were randomly allocated into two treatment groups: SI with EAF or SI alone. Clinical parameters of percentage of probing pocket depths (PPDs) of ≥5 mm, full mouth bleeding and plaque scores (FMBS and FMPS), and PPD values were recorded at baseline, and at 3 and 6 months posttreatment. A visual analogue scale was used to evaluate postoperative participants' perception of pain, swelling, bleeding, bruising, and root sensitivity. The impact of periodontal treatment on quality of life was assessed using the General Oral Health Assessment Index (GOHAI) at six months.
A total of 26 participants with Stage III/IV periodontitis completed the 6-month follow-up. SI with or without EAF resulted in a statistically significant reductions in the FMBS, FMPS, PPDs, and percentage of PPDs of ≥5 mm at the 3- and 6-month follow-up visits. There was no statistically significant difference between the two treatment groups for any time interval. Participants receiving SI/EAF exhibited a higher reduction in FMBS compared to those in SI alone group at 3 (SI/EAF: 19.4 ± 11.9, SI alone: 30.1 ± 20.5; P = 0.12) and 6 months (SI/EAF: 14.3 ± 9.6, SI alone: 24.5 ± 18.2; P = 0.09). A lower percentage of sites with deep PPDs (≥5 mm) was also noted amongst participants in the SI/EAF group compared to SI alone at 3 months (SI/EAF: 14.3 ± 14.1, SI alone: 19.2 ± 20.3; P = 0.48) and 6 months (SI/EAF: 8.3 ± 10.0, SI alone: 15.4 ± 17.4; P = 0.22). Patient-reported outcomes showed no significant differences between the two treatment groups, except in the psychosocial domain of the GOHAI at 6 months favoring the SI/EAF group (P = 0.03).
Within the limitations of the study, the adjunctive use of EAF in addition to SI in the treatment of Stage III/IV periodontitis did not result in a significant improvement in clinical parameters. Limited improvement in the QoL with EAF could be achieved.
本随机对照试验的目的是评估在牙周炎治疗中,与单纯龈下器械操作(SI)相比,辅助使用赤藓糖醇气流(EAF)进行龈下器械操作的临床和患者报告结局。
26名需要进行非手术牙周治疗的III/IV期牙周炎患者被随机分为两个治疗组:SI联合EAF组或单纯SI组。在基线、治疗后3个月和6个月时记录探诊深度(PPD)≥5mm的百分比、全口出血和菌斑评分(FMBS和FMPS)以及PPD值等临床参数。使用视觉模拟量表评估术后参与者对疼痛、肿胀、出血、瘀伤和牙根敏感的感受。在6个月时使用一般口腔健康评估指数(GOHAI)评估牙周治疗对生活质量的影响。
共有26名III/IV期牙周炎患者完成了6个月的随访。在3个月和6个月的随访中,无论是否联合EAF,SI均使FMBS、FMPS、PPD以及PPD≥5mm的百分比有统计学意义的降低。两个治疗组在任何时间间隔均无统计学显著差异。在3个月(SI/EAF组:19.4±11.9,单纯SI组:30.1±20.5;P=0.12)和6个月(SI/EAF组:14.3±9.6,单纯SI组:24.5±18.2;P=0.09)时,接受SI/EAF治疗的参与者FMBS降低幅度高于单纯SI组。在3个月(SI/EAF组:14.3±14.1,单纯SI组:19.2±20.3;P=0.48)和6个月(SI/EAF组:8.3±10.0,单纯SI组:15.4±17.4;P=0.22)时,SI/EAF组深PPD(≥5mm)部位的百分比也低于单纯SI组。患者报告结局显示,两个治疗组之间无显著差异,但在6个月时GOHAI的心理社会领域中,SI/EAF组更具优势(P=0.03)。
在本研究的局限性范围内,在治疗III/IV期牙周炎时,除SI外辅助使用EAF并未使临床参数有显著改善。使用EAF可在生活质量方面实现有限改善。