Department of Cariology, Endodontology and Periodontology, Centre for Periodontology, University Hospital of Leipzig, Liebigstr. 12, Haus 1, 04103, Leipzig, Germany.
Private Dental Practice, Berlin, Germany.
BMC Oral Health. 2020 Dec 29;20(1):364. doi: 10.1186/s12903-020-01363-5.
This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis.
Fourty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n = 21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n = 21). They were analyzed for the clinical variables BOP (primary outcome at six months), probing depth (PD), attachment level, four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons.
In both groups, the clinical variables PD, attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5 mm was significantly lower in the test group than in the control group after six months. At six months versus baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group.
Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5 mm when compared with subgingival instrumentation only.
The adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery. Trial registration The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL .
本研究旨在探究在龈下刮治期间辅助使用喷嘴系统添加的赤藓糖醇空气抛光粉是否会影响中重度牙周炎患者非手术牙周治疗的结果。
42 名牙周炎患者接受非手术牙周治疗，其中 21 名患者（对照组）在龈下刮治期间不使用附加空气抛光，21 名患者（试验组）使用喷嘴+赤藓糖醇粉进行辅助空气抛光。在基线时、龈下刮治前以及龈下刮治后 3 个月和 6 个月时，对所有患者的探诊出血（主要结局指标，6 个月时）、探诊深度（PD）、附着水平、四种选定的微生物和两种生物标志物进行分析。统计分析包括组内和组间的非参数检验。
两组患者的 PD、附着水平和探诊出血在龈下刮治后 3 个月和 6 个月时均显著改善。与对照组相比，试验组在 6 个月时 PD≥5mm 的位点数量明显减少。与基线相比，试验组在 6 个月时，福赛坦纳氏菌和牙髓密螺旋体的数量明显减少，MMP-8 水平也较低。
龈下刮治联合赤藓糖醇空气抛光粉并不能降低探诊出血。但与单纯龈下刮治相比，它可能会带来有益的效果，如减少 PD≥5mm 的牙周袋残留数量，从而改善龈下刮治的临床效果。
在龈下刮治期间使用喷嘴系统添加赤藓糖醇空气抛光粉可能会改善龈下刮治的临床效果，并可能减少牙周手术的需求。
该研究于 2018 年 8 月 6 日在德国临床试验注册中心 DRKS00015239 进行了回顾性注册，网址为 https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL。
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