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血液透析患者血清钾的季节性变化:是真是假?文献综述。

Seasonal variation of serum potassium in hemodialysis patients: myth or reality? A narrative review of literature.

机构信息

Department of Family Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, PR China.

出版信息

Ren Fail. 2024 Dec;46(2):2359640. doi: 10.1080/0886022X.2024.2359640. Epub 2024 Jun 4.

DOI:10.1080/0886022X.2024.2359640
PMID:38832483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11151801/
Abstract

Research has shown that patients undergoing hemodialysis experience seasonal variations in their serum potassium levels. There was inconsistent seasonal fluctuation in serum potassium levels among the hemodialysis population across different locations. In the form of narrative review for the first time, the article discusses the seasonal changes of serum potassium in this population and its potential reasons, this article demonstrates that it is primarily attributable to seasonal dietary potassium intake. However, existing studies have not quantified seasonal dietary potassium intake, so the results are still speculative. Furthermore, future research ought to further expound upon the clinical implications of seasonal variations in serum potassium levels among dialysis patients, as well as other influencing mechanisms such as the pathophysiological causes of these seasonal changes, particularly those pertaining to dietary, geographical, and regional factors. These findings contribute to a more thorough interpretation of laboratory results in hemodialysis patients and provide important guidance for their individualized dietary management.

摘要

研究表明,接受血液透析的患者其血清钾水平存在季节性变化。不同地区的血液透析人群的血清钾水平存在不一致的季节性波动。本文首次以叙述性综述的形式讨论了该人群血清钾的季节性变化及其潜在原因,表明主要归因于季节性膳食钾摄入。然而,现有研究尚未量化季节性膳食钾摄入,因此结果仍具有推测性。此外,未来的研究应该进一步阐述透析患者血清钾水平季节性变化的临床意义,以及其他影响机制,如这些季节性变化的病理生理原因,特别是与饮食、地理和地区因素有关的原因。这些发现有助于更全面地解释血液透析患者的实验室结果,并为其个体化饮食管理提供重要指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1dd/11151801/249694ead421/IRNF_A_2359640_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1dd/11151801/249694ead421/IRNF_A_2359640_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1dd/11151801/249694ead421/IRNF_A_2359640_F0001_B.jpg

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本文引用的文献

1
Association between annual variability of potassium levels and prognosis in patients undergoing hemodialysis.血钾水平年度变化与血液透析患者预后的关系。
Clin Exp Nephrol. 2023 Oct;27(10):873-881. doi: 10.1007/s10157-023-02368-4. Epub 2023 Jun 15.
2
Chronic Hyperkaliemia in Chronic Kidney Disease: An Old Concern with New Answers.慢性肾脏病中的慢性高钾血症:旧有担忧,新有答案。
Int J Mol Sci. 2022 Jun 7;23(12):6378. doi: 10.3390/ijms23126378.
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Potassium Intake-(Un)Expected Non-Predictor of Higher Serum Potassium Levels in Hemodialysis DASH Diet Consumers.
低钾摄入-(非)意料之外的血液透析 DASH 饮食消费者高血钾的非预测因素。
Nutrients. 2022 May 15;14(10):2071. doi: 10.3390/nu14102071.
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Prevalence, recurrence and seasonal variation of hyperkalemia among patients on hemodialysis.血液透析患者高钾血症的患病率、复发率及季节性变化
Int Urol Nephrol. 2022 Sep;54(9):2327-2334. doi: 10.1007/s11255-022-03142-3. Epub 2022 Feb 8.
5
Serum Potassium and Mortality Risk in Hemodialysis Patients: A Cohort Study.血液透析患者的血清钾水平与死亡风险:一项队列研究
Kidney Med. 2021 Oct 22;4(1):100379. doi: 10.1016/j.xkme.2021.08.013. eCollection 2022 Jan.
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Dietary Potassium Intake and All-Cause Mortality in Adults Treated with Hemodialysis.饮食钾摄入量与血液透析患者全因死亡率的关系。
Clin J Am Soc Nephrol. 2021 Dec;16(12):1851-1861. doi: 10.2215/CJN.08360621. Epub 2021 Dec 1.
7
Potassium Metabolism and Management in Patients with CKD.慢性肾脏病患者的钾代谢和管理。
Nutrients. 2021 May 21;13(6):1751. doi: 10.3390/nu13061751.
8
Different Seasonal Variations of Potassium in Hemodialysis Patients with High Longitudinal Potassium Levels: A Multicenter Cohort Study Using DialysisNet.多中心队列研究使用 DialysisNet 观察血钾水平较高的血液透析患者血钾的季节性变化差异。
Yonsei Med J. 2021 Apr;62(4):315-324. doi: 10.3349/ymj.2021.62.4.315.
9
Does dietary potassium intake associate with hyperkalemia in patients with chronic kidney disease?膳食钾摄入与慢性肾脏病患者高钾血症有关吗?
Nephrol Dial Transplant. 2021 Nov 9;36(11):2049-2057. doi: 10.1093/ndt/gfaa232.
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