Department of Psychiatry, Fundación Jiménez Díaz University Hospital, Madrid, Spain.
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Madrid, Spain.
Curr Psychiatry Rep. 2024 Jul;26(7):379-393. doi: 10.1007/s11920-024-01512-5. Epub 2024 Jun 4.
The assessment of the risk of triggering psychosis upon exposure to grief is a challenge in clinical practice. Adequate diagnosis and early prevention are essential and may be helpful in the evolution of normal grief. We aimed to identify studies exploring grief as a risk factor for developing psychosis.
A systematic review of 3 databases (PubMed, EMBASE, and Cochrane Library) was conducted.
In the first approach 618 studies were identified. After the selection process, 15 studies were included in the review. The association between grief and the risk of developing psychosis occurred at younger ages (before 18 years of age) in a first-degree relative and as a consequence of suicide or accidental death. We found that risk factors such as comorbidity, mental problems, unemployment, economic difficulties, and close ties with the deceased have a negative impact on health causing greater vulnerability to psychosis with a risk of developing complicated grief, with statistically significant results regarding the associations between early parental death and the probability of developing psychosis in adulthood.
接触悲痛时引发精神病的风险评估在临床实践中是一个挑战。充分的诊断和早期预防至关重要，可能有助于正常悲痛的发展。我们旨在确定探索悲痛作为发展精神病风险因素的研究。
对 3 个数据库（PubMed、EMBASE 和 Cochrane Library）进行了系统综述。
在第一种方法中，确定了 618 项研究。经过选择过程，有 15 项研究被纳入综述。悲痛与精神病风险之间的关联发生在年龄较小（18 岁之前）的一级亲属中，并且是自杀或意外死亡的结果。我们发现，共存病症、精神问题、失业、经济困难和与死者的密切关系等风险因素对健康有负面影响，导致精神病的脆弱性更大，并且与成年后患精神病的概率之间存在早逝父母的关联具有统计学意义。
